# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5054275 | F | Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA5054276 | F | Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
3. | ALA5054277 | B | Protac activity at VHL/BCL-XL in human MOLT-4 assessed as decrease in BCL-XL protein level at up to 1000 uM measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
4. | ALA5054278 | B | Protac activity at VHL/BCL-XL in human RS4-11 assessed as decrease in BCL-XL protein level at up to 1000 uM measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
5. | ALA5054292 | B | Binding affinity to Halo-tagged VHL/HiBiT-tagged BCL-XL (unknown origin) expressed in HEK293T cells assessed as ternary complex formation at up to 100000 nM measured after 6 hrs by NanoBRET assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA5054293 | B | Binding affinity to Halo-tagged VHL/HiBiT-tagged BCL-2 (unknown origin) expressed in HEK293T cells assessed as ternary complex formation at up to 100000 nM measured after 6 hrs by NanoBRET assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA5054295 | B | Binding affinity to VHL/ BCL-XL in human RS4-11 cells assessed as ternary complex formation at up to 300 nM measured after 12 hrs by immunoprecipitation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA5054296 | B | Binding affinity to VHL/BCL-2 in human RS4-11 cells assessed as ternary complex formation at up to 300 nM measured after 12 hrs by immunoprecipitation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA5054297 | B | Binding affinity to VHL/ BCL-XL in human RS4-11 cells assessed as ternary complex formation at up to 300 nM measured after 12 hrs in presence of VHL-032 by immunoprecipitation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA5054298 | B | Binding affinity to VHL/BCL-2 in human RS4-11 cells assessed as ternary complex formation at up to 300 nM measured after 12 hrs in presence of VHL-032 by immunoprecipitation assay | Homo sapiens | 4 | cell-based format | Scientific Literature |