#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5054798	Binding	Binding affinity to human recombinant ACE protein assessed as dissociation constant incubated for 15 mins by MTS binding analysis	Homo sapiens	2	ALA5053532	single protein format	Scientific Literature
2.	ALA5054801	ADME	Stability of the compound in rat plasma assessed as drug residual at 10 uM measured after 48 hrs by LC/MS analysis	Rattus norvegicus	1	ALA5053532	cell-free format	Scientific Literature
3.	ALA5054802	ADME	Stability of the compound in rat plasma assessed as PTX release at steady state at 10 uM measured after 72 hrs by LC/MS analysis	Rattus norvegicus	1	ALA5053532	cell-free format	Scientific Literature
4.	ALA5054803	ADME	Stability of the compound in rat plasma assessed as half life at 10 uM measured after 72 hrs by LC/MS analysis	Rattus norvegicus	1	ALA5053532	cell-free format	Scientific Literature
5.	ALA5054804	Physicochemical	Stability of the compound in PBS buffer assessed as half life at 10 uM measured after 72 hrs by LC/MS analysis		1	ALA5053532	small-molecule physicochemical format	Scientific Literature
6.	ALA5054805	Functional	Antiproliferative activity against ACE-negative human HEK293T cells incubated for 48 hrs by MTT assay	Homo sapiens	2	ALA5053532	cell-based format	Scientific Literature
7.	ALA5054806	Functional	Antiproliferative activity against ACE-positive human MDA-MB-231 cells incubated for 48 hrs by MTT assay	Homo sapiens	2	ALA5053532	cell-based format	Scientific Literature
8.	ALA5054807	Functional	Antiproliferative activity against ACE-positive human MDA-MB-468 cells incubated for 48 hrs by MTT assay	Homo sapiens	2	ALA5053532	cell-based format	Scientific Literature
9.	ALA5054808	Functional	Antiproliferative activity against human HEK293T cells expressing ACE containing plasmid incubated for 48 hrs by MTT assay	Homo sapiens	1	ALA5053532	cell-based format	Scientific Literature
10.	ALA5054809	ADME	Drug uptake in human MDA-MB-468 cells assessed as increase in PTX uptake rate at 10 to 20 uM measured after 2 hrs	Homo sapiens	1	ALA5053532	cell-based format	Scientific Literature
11.	ALA5054811	Functional	Induction of apoptosis in ACE-positive human MDA-MB-231 cells assessed as increase in apoptotic cells at 10 nM measured after 48 hrs by Annexin V-FITC/PI staining based fluorescence microscopy	Homo sapiens	2	ALA5053532	cell-based format	Scientific Literature
12.	ALA5054812	Functional	Induction of apoptosis in ACE-positive human MDA-MB-468 cells assessed as increase in apoptotic cells at 10 nM measured after 48 hrs by Annexin V-FITC/PI staining based fluorescence microscopy	Homo sapiens	2	ALA5053532	cell-based format	Scientific Literature
13.	ALA5054815	Toxicity	Acute toxicity in BALB/c mouse assessed as rate of weight loss at 60 mg/kg, ip measured for 15 days	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
14.	ALA5054816	Toxicity	Acute toxicity in BALB/c mouse assessed as rate of weight loss at 80 mg/kg, ip measured for 15 days	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
15.	ALA5054817	Toxicity	Acute toxicity in BALB/c mouse assessed as rate of weight loss at 100 mg/kg, ip measured for 15 days	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
16.	ALA5054820	Toxicity	Acute toxicity in BALB/c mouse assessed as survival at 60 mg/kg, ip measured for 15 days	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
17.	ALA5054821	Toxicity	Acute toxicity in BALB/c mouse assessed as survival at 80 mg/kg, ip measured for 15 days	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
18.	ALA5054822	Toxicity	Acute toxicity in BALB/c mouse assessed as survival at 100 mg/kg, ip measured for 15 days	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
19.	ALA5054823	ADME	Drug uptake in BALB/c mouse xenografted with human MBA-MD-468 cells assessed as PTX level in tumor at 17.6 micromol/kg, ip measured after 1 hr	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature
20.	ALA5054826	ADME	Drug uptake in BALB/c mouse xenografted with human MBA-MD-468 cells assessed as PTX level in tumor at 17.6 micromol/kg, ip measured after 4 hrs	Mus musculus	1	ALA5053532	organism-based format	Scientific Literature