| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5050624 | B | Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 60 mins by Kinase-GLO reagent based assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 2. | ALA5050625 | F | Antiproliferative activity against human MOG-G-UVW cells assessed as inhibition of cell proliferation incubated for 72 hrs by cell titer-Glo assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 3. | ALA5050627 | A | Drug metabolism in rat liver microsomes assessed as GSH-adduct formation at 1 mg/ml and measured after 60 mins in presence of glutathione and NADPH by ion chromatogram analysis relative to control | Rattus norvegicus | 24 | microsome format | Scientific Literature | ||
| 4. | ALA5050629 | A | Drug metabolism in human liver microsomes assessed as GSH-adduct formation at 1 mg/ml and measured after 60 mins in presence of glutathione and NADPH by ion chromatogram analysis relative to control | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 5. | ALA5050632 | A | Substrate activity at P-gp (unknown origin) transfected in LLC-PK1 cells expressing human MDR1 gene assessed as efflux ratio of permeability across basolateral to apical membrane at 0.1 uM | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 6. | ALA5050645 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 16 | microsome format | Scientific Literature | ||
| 7. | ALA5050646 | A | Drug metabolism in dog liver microsomes assessed as glutathione-adduct formation measured after 60 mins in presence of NADPH | Canis lupus familiaris | 3 | microsome format | Scientific Literature |
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