# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5043203 | B | Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assay | Homo sapiens | 40 | ALA5042486 | single protein format | Scientific Literature | |
2. | ALA5043205 | B | Inhibition of CD69 in human whole blood preincubated for 30 mins followed by anti-human IgD stimulation and measured after 18 to 22 hrs by flow cytometry | Homo sapiens | 27 | ALA5042486 | tissue-based format | Scientific Literature | |
3. | ALA5043206 | P | Kinetic aqueous solubility of the compound in pH 6.8 | 16 | ALA5042486 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5043208 | A | Clearance in rat liver microsomes assessed as hepatic blood flow | Rattus norvegicus | 13 | ALA5042486 | microsome format | Scientific Literature | |
5. | ALA5043209 | A | Clearance in human liver microsomes assessed as hepatic blood flow | Homo sapiens | 13 | ALA5042486 | microsome format | Scientific Literature | |
6. | ALA5043210 | A | Protein binding in human plasma assessed as unbound fraction at 2 uM by rapid equilibrium dialysis method | Homo sapiens | 13 | ALA5042486 | cell-free format | Scientific Literature | |
7. | ALA5043211 | P | Kinetic solubility of the compound at pH 1.5 by shake flask method | 13 | ALA5042486 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA5043213 | P | Lipophilicity, logD of the compound at pH 7.6 by shake flask assay | 13 | ALA5042486 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA5043292 | P | Dissociation constant, pKa of the compound | 4 | ALA5042486 | small-molecule physicochemical format | Scientific Literature |