# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5033029 | B | Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as fold decrease in reporter activity at 100 uM measured after 14 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA5033030 | B | Inverse agonist activity at full length TLX activating element expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as fold decrease in reporter activity at 100 uM by luciferase reporter gene assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA5033031 | B | Stabilization of human recombinant TLX LBD assessed as change in melting temperature at 500 uM by DSF assay | Homo sapiens | 14 | single protein format | Scientific Literature |