# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5039651 | B | Inhibition of human ABL G250E mutant using EAIYAAPFAKKK as substrate assessed as residual activity at 10 nM incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liquid scintillation counter method relative to control | Homo sapiens | 2 | ALA5038588 | single protein format | Scientific Literature | |
2. | ALA5039652 | F | Cytotoxicity against mouse BAF3 cells expressing native BCR-ABL assessed as inhibition of cell growth measured after 72 hrs by MTT assay | Mus musculus | 10 | ALA5038588 | cell-based format | Scientific Literature | |
3. | ALA5039655 | F | Cytotoxicity against mouse BAF3 cells expressing BCR-ABL T315I mutant assessed as inhibition of cell growth measured after 48 hrs by trypan blue assay | Mus musculus | 10 | ALA5038588 | cell-based format | Scientific Literature | |
4. | ALA5039656 | F | Cytotoxicity against human K562 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay | Homo sapiens | 10 | ALA5038588 | cell-based format | Scientific Literature | |
5. | ALA5039657 | F | Cytotoxicity against human KU812 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay | Homo sapiens | 10 | ALA5038588 | cell-based format | Scientific Literature | |
6. | ALA5039658 | F | Cytotoxicity against human U-937 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay | Homo sapiens | 10 | ALA5038588 | cell-based format | Scientific Literature | |
7. | ALA5039659 | F | Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay | Homo sapiens | 10 | ALA5038588 | cell-based format | Scientific Literature | |
8. | ALA5039660 | F | Cytotoxicity against human K562 cells assessed as induction of cell death | Homo sapiens | 2 | ALA5038588 | cell-based format | Scientific Literature | |
9. | ALA5039661 | F | Cytotoxicity against mouse BAF3 cells expressing BCR-ABL T315I mutant assessed as induction of cell death | Mus musculus | 1 | ALA5038588 | cell-based format | Scientific Literature | |
10. | ALA5039662 | B | Inhibition of BCR-ABL phosphorylation at tyrosine 245 residue in human K562 cells at upto 1000 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 2 | ALA5038588 | cell-based format | Scientific Literature | |
11. | ALA5039663 | B | Inhibition of BCR-ABL phosphorylation at tyrosine 245 residue in mouse BaF3 cells at upto 1000 nM measured after 4 hrs by Western blot analysis | Mus musculus | 2 | ALA5038588 | cell-based format | Scientific Literature | |
12. | ALA5039664 | B | Inhibition of BCR-ABL phosphorylation at tyrosine 245 residue in mouse BaF3 cells expressing T315I mutant at up to 1000 nM measured after 4 hrs by Western blot analysis | Mus musculus | 2 | ALA5038588 | cell-based format | Scientific Literature | |
13. | ALA5039665 | B | Inhibition of CRKL phosphorylation at tyrosine 207 residue in human K562 cells expressing BCR-ABL at upto 1000 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA5038588 | cell-based format | Scientific Literature | |
14. | ALA5039666 | B | Inhibition of CRKL phosphorylation at tyrosine 207 residue in mouse BaF3 cells expressing BCR-ABL at upto 1000 nM measured after 4 hrs by Western blot analysis | Mus musculus | 1 | ALA5038588 | cell-based format | Scientific Literature | |
15. | ALA5039667 | B | Inhibition of CRKL phosphorylation at tyrosine 207 residue in mouse BaF3 cells expressing BCR-ABL T315I mutant at upto 1000 nM measured after 4 hrs by Western blot analysis | Mus musculus | 1 | ALA5038588 | cell-based format | Scientific Literature | |
16. | ALA5039672 | T | Inhibition of hERG | Homo sapiens | 2 | ALA5038588 | assay format | Scientific Literature | |
17. | ALA5039673 | T | Mutagenecity in Salmonella typhimurium TA97a at 0.5 to 312.5 ug/ml incubated for 42 to 72 hrs in presence of S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA5038588 | organism-based format | Scientific Literature | |
18. | ALA5039674 | T | Mutagenecity in Salmonella typhimurium TA98 at 0.5 to 312.5 ug/ml incubated for 42 to 72 hrs in presence of S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA5038588 | organism-based format | Scientific Literature | |
19. | ALA5039675 | T | Mutagenecity in Salmonella typhimurium TA102 at 0.5 to 312.5 ug/ml incubated for 42 to 72 hrs in presence of S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA5038588 | organism-based format | Scientific Literature | |
20. | ALA5039676 | T | Mutagenecity in Salmonella typhimurium TA100 at 0.5 to 312.5 ug/ml incubated for 42 to 72 hrs in presence of S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA5038588 | organism-based format | Scientific Literature |