# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5039228 | F | Antiviral activity against wild type Rhinovirus-A02 infected in HeLa cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS/PMS assay | Rhinovirus | 4 | ALA5038578 | cell-based format | Scientific Literature | |
2. | ALA5039229 | F | Antiviral activity against wild type Human rhinovirus B14 infected in HeLa cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS/PMS assay | rhinovirus B14 | 4 | ALA5038578 | organism-based format | Scientific Literature | |
3. | ALA5039230 | B | Inhibition of Human enterovirus 71 3C-like protease expressed in Escherichia coli BL21 (DE3) cells using Dacyl-KTSAVLQSGFRKMEEdans as fluorogenic substrate incubated for 10 mins by FRET assay | Enterovirus A71 | 24 | ALA5038578 | cell-based format | Scientific Literature | |
4. | ALA5039231 | F | Antiviral activity against Human enterovirus 71 BrCr infected in human RD cells assessed as reduction in virus-induced cytopathic effect incubated for 4 days by MTS/PMS assay | Enterovirus A71 | 24 | ALA5038578 | organism-based format | Scientific Literature | |
5. | ALA5039232 | T | Cytotoxicity against human RD cells assessed as reduction in cell viability measured after 4 days by MTS/PMS assay | Homo sapiens | 24 | ALA5038578 | cell-based format | Scientific Literature | |
6. | ALA5039233 | F | Antiviral activity against Human enterovirus 68 infected in HeLa cells assessed as reduction in virus-induced cytopathic effect incubated for 4 days by MTS/PMS assay | enterovirus D68 | 4 | ALA5038578 | organism-based format | Scientific Literature | |
7. | ALA5039234 | F | Antiviral activity against Human coxsackievirus A21 infected in HeLa cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS/PMS assay | Coxsackievirus A21 | 4 | ALA5038578 | organism-based format | Scientific Literature | |
8. | ALA5039235 | F | Antiviral activity against Human coxsackievirus B3 infected in Vero cells assessed as reduction in plaque formation treated 2 hrs post viral infection and measured 3 to 4 days post-infection by Giemsa staining based plaque reduction assay | Coxsackievirus B3 | 4 | ALA5038578 | organism-based format | Scientific Literature | |
9. | ALA5039255 | B | Inhibition of SARS-CoV2 3C-like protease expressed in Escherichia coli BL21 (DE3) cells using Mca-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorogenic substrate incubated for 10 mins by FRET assay | Severe acute respiratory syndrome coronavirus 2 | 13 | ALA5038578 | cell-based format | Scientific Literature | |
10. | ALA5039256 | F | Antiviral activity against SARS Cov-2 infected in Vero E6 cells assessed as reduction in viral RNA replication measured 24 hrs post infection by qRT-PCR analysis | Severe acute respiratory syndrome coronavirus 2 | 13 | ALA5038578 | organism-based format | Scientific Literature | |
11. | ALA5039257 | T | Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Chlorocebus sabaeus | 13 | ALA5038578 | cell-based format | Scientific Literature |