# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5051761 | B | Inhibition of METTL3 (unknown origin) using UCUGGACUAAA-biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 30 mins by TopCount scintillation counting method | Homo sapiens | 222 | single protein format | Patent Bioactivity Data | ||
2. | ALA5051762 | B | Inhibition of PRMT5 (unknown origin) using Ac-SGRGKGGKGLGKGGAKRHRKVGGK-Biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 60 mins by TopCount scintillation counting method | Homo sapiens | 221 | single protein format | Patent Bioactivity Data | ||
3. | ALA5051763 | B | Inhibition of METTL1 (unknown origin) using GCCGAGAUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGUCCCUG GUUCAAUCCCGGGUUUCGGCA-biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 20 mins by TopCount scintillation counting method | Homo sapiens | 143 | assay format | Patent Bioactivity Data | ||
4. | ALA5051765 | B | Inhibition of METTL3-mediated m6A methylation in human MOLM-13 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis | Homo sapiens | 50 | cell-based format | Patent Bioactivity Data | ||
5. | ALA5051766 | F | Antiproliferative activity against human MOLM-13 cells after 48 hrs by Cell Titer-Glo assay | Homo sapiens | 65 | cell-based format | Patent Bioactivity Data | ||
6. | ALA5051767 | F | Antiproliferative activity against human MOLM-13 cells after 96 hrs by Cell Titer-Glo assay | Homo sapiens | 71 | cell-based format | Patent Bioactivity Data |