# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5056844 | Binding | Binding affinity to human BRD3 domain 1 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
2. | ALA5056845 | Binding | Binding affinity to human BRD2 domain 2 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
3. | ALA5056846 | Binding | Binding affinity to human BRD2 domain 1 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
4. | ALA5056850 | Binding | Binding affinity to human BRD4 domain 1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 14 | ALA5055650 | single protein format | Scientific Literature | |
5. | ALA5056851 | Binding | Inhibition of human recombinant HDAC6 assessed as fluorescence using fluorogenic substrate ZMAL incubated for 90 min by microplate reader | Homo sapiens | 14 | ALA5055650 | single protein format | Scientific Literature | |
6. | ALA5056852 | Binding | Inhibition of human recombinant HDAC1 assessed as fluorescence using fluorogenic substrate ZMAL incubated for 90 min by microplate reader | Homo sapiens | 14 | ALA5055650 | single protein format | Scientific Literature | |
7. | ALA5056853 | Binding | Binding affinity to human BRD3 domain 2 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
8. | ALA5056854 | Binding | Binding affinity to human BRD7 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
9. | ALA5056855 | Binding | Inhibition of human HDAC2 assessed as target activity using fluorogenic substrate ZMAL for 90 min by microplate reader at 355nm | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
10. | ALA5056856 | Binding | Inhibition of human HDAC3 assessed as target activity using fluorogenic substrate ZMAL for 90 min by microplate reader at 355nm | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
11. | ALA5056857 | Functional | Anticancer activity against human HPBALL cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
12. | ALA5056858 | Functional | Anticancer activity against human TALL-1 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
13. | ALA5056859 | Functional | Anticancer activity against human HL-60 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
14. | ALA5056860 | Functional | Anticancer activity against human K562 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
15. | ALA5056861 | Functional | Anticancer activity against human HAL-01 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
16. | ALA5056862 | Functional | Anticancer activity against human REH cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
17. | ALA5056871 | Binding | Inhibition of HDAC in human K562 cells assessed as decrease in MYC expression measured after 24 to 72 hrs by Western blot analysis | Homo sapiens | 4 | ALA5055650 | cell-based format | Scientific Literature | |
18. | ALA5056879 | Binding | Inhibition of HDAC in human K562 cells assessed as increase in acetylated alpha-tubulin measured after 48 hrs by Western blot analysis | Homo sapiens | 4 | ALA5055650 | cell-based format | Scientific Literature | |
19. | ALA5056880 | Binding | Inhibition of HDAC in human K562 cells assessed as increase in acetylated histone H3 measured after 48 hrs by Western blot analysis | Homo sapiens | 4 | ALA5055650 | cell-based format | Scientific Literature |