# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5053965 | Binding | Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oligonucleotide substrate by TR-FRET assay | Homo sapiens | 23 | ALA5053501 | cell-based format | Scientific Literature | |
2. | ALA5053966 | Physicochemical | Kinetic solubility of the compound in PBS at pH 7.4 at 100 uM incubated for 1 hr by LCMS/MS analysis | 22 | ALA5053501 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5053967 | ADME | Efflux ratio of apparent permeability in human Caco-2 cells at 10 uM measured after 90 mins using fluorometry | Homo sapiens | 22 | ALA5053501 | cell-based format | Scientific Literature | |
4. | ALA5053968 | ADME | Metabolic stability in rat liver microsomes assessed as half life by LC-MS analysis | Rattus norvegicus | 22 | ALA5053501 | microsome format | Scientific Literature | |
5. | ALA5053988 | ADME | Apparent permeability of the compound across apical to basolateral side in human Caco-2 cells at 10 uM measured after 90 mins by LC-MS/MS system | Homo sapiens | 22 | ALA5053501 | cell-based format | Scientific Literature |