# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5111620 | B | Binding affinity to recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as change in melting temperature at 10 uM by differential scanning fluorimetry | Homo sapiens | 29 | ALA5108049 | cell-based format | Scientific Literature | |
2. | ALA5111621 | B | Binding affinity to recombinant LIMK2 (330 to 632 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as change in melting temperature at 10 uM by differential scanning fluorimetry | Homo sapiens | 29 | ALA5108049 | cell-based format | Scientific Literature | |
3. | ALA5111623 | B | Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of tracer K10 by NanoBRET assay | Homo sapiens | 17 | ALA5108049 | cell-based format | Scientific Literature | |
4. | ALA5111624 | B | Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of tracer K10 by NanoBRET assay | Homo sapiens | 17 | ALA5108049 | cell-based format | Scientific Literature | |
5. | ALA5111625 | B | Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ATP by RapidFire mass spectrometry | Homo sapiens | 4 | ALA5108049 | cell-based format | Scientific Literature | |
6. | ALA5111626 | B | Inhibition of recombinant LIMK2 (330 to 632 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ATP by RapidFire mass spectrometry | Homo sapiens | 4 | ALA5108049 | cell-based format | Scientific Literature | |
7. | ALA5111627 | B | Inhibition of LIMK1 in human HeLa cells lysate incubated for 45 mins by kinobead based pulldown assay | Homo sapiens | 3 | ALA5108049 | subcellular format | Scientific Literature | |
8. | ALA5111628 | B | Inhibition of LIMK2 in human HeLa cells lysate incubated for 45 mins by kinobead based pulldown assay | Homo sapiens | 3 | ALA5108049 | subcellular format | Scientific Literature | |
9. | ALA5111629 | B | Binding affinity to LIMK1 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assay | Homo sapiens | 3 | ALA5108049 | cell-based format | Scientific Literature | |
10. | ALA5111630 | B | Binding affinity to LIMK2 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assay | Homo sapiens | 3 | ALA5108049 | cell-based format | Scientific Literature | |
11. | ALA5111633 | F | Inhibition of neurite outgrowth in BMP7 stimulated mouse N1E-115 cells transfected with siFMR1 preincubated for 12 hrs followed by BMP7 stimulation for 24 hrs | Mus musculus | 4 | ALA5108049 | cell-based format | Scientific Literature | |
12. | ALA5111635 | F | Upregulation of ANLN expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
13. | ALA5111636 | F | Upregulation of EPB41L1 expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
14. | ALA5111638 | F | Upregulation of CAP2 expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
15. | ALA5111639 | F | Upregulation of FLNA expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
16. | ALA5111640 | F | Upregulation of DPYSL3 expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
17. | ALA5111641 | F | Upregulation of CAP1 expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
18. | ALA5111642 | F | Upregulation of ARHGAP21 expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
19. | ALA5111643 | F | Upregulation of CALD1 expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature | |
20. | ALA5111644 | F | Upregulation of ABLIMI expression in human HeLa cells assessed as fold increase at 100 uM incubated for 30 mins by phosphoproteomic analysis | Homo sapiens | 2 | ALA5108049 | cell-based format | Scientific Literature |