# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5138117 | T | Selectivity index, ratio of CC50 for cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level to EC50 for antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as reduction of viral replication | 19 | ALA5136987 | cell-based format | Scientific Literature | ||
2. | ALA5138118 | F | Antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as reduction of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepacivirus hominis | 21 | ALA5136987 | organism-based format | Scientific Literature | |
3. | ALA5138119 | T | Cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level measured after 72 hrs by Glo-max luminescence based assay | Homo sapiens | 21 | ALA5136987 | cell-based format | Scientific Literature | |
4. | ALA5138120 | F | Antiviral activity against HCV 3a S52 in human Huh7.5 cells carrying HCV subgenomic replicons assessed as inhibition of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA5136987 | organism-based format | Scientific Literature | |
5. | ALA5138122 | F | Antiviral activity against HCV 2a JFH1 in human Huh-7 cells carrying HCV subgenomic replicon assessed as inhibition of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepatitis C virus | 6 | ALA5136987 | cell-based format | Scientific Literature | |
6. | ALA5138123 | F | Antiviral activity against HCV 4a ED43 in human Huh7.5 cells carrying HCV subgenomic replicon assessed as inhibition of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA5136987 | organism-based format | Scientific Literature |