| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5098382 | B | Inhibition of BTK (unknown origin) incubated 30 mins by FRET assay | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 2. | ALA5098387 | T | Antiproliferative activity against human PBMC preincubated for 30 mins followed by IL-4 stimulation for 3 days by cell titer glo assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 3. | ALA5098394 | B | Binding affinity to human partial length TEC (L341 to D620 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 4. | ALA5098395 | B | Binding affinity to human partial length ITK (R335 to L620 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 5. | ALA5098396 | B | Binding affinity to human partial length TXK (L238 to W527 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 6. | ALA5098397 | B | Binding affinity to human full length BMX (M1 to H675 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 7. | ALA5098400 | A | Clearance in iv dosed Sprague Dawley rat assessed as hepatic blood flow | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA5098402 | B | Inhibition of CD69 (unknown origin) in PBMC preincubated for 30 mins followed by IL-4 stimulation for 3 days by cell titer glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA5098405 | A | Plasma protein binding in human assessed as unbound fraction at 2 uM by rapid equilibrium dialysis analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 10. | ALA5098406 | A | Plasma protein binding in rat assessed as unbound fraction at 2 uM by rapid equilibrium dialysis analysis | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
| 11. | ALA5098409 | A | Apparent permeability of compound across Caco-2/TC-7 monolayers in human Caco-2 cells by LC/MSMS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5098410 | A | Inhibition of CYP3A4 (unknown origin) using testosterone as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5098411 | A | Permeability of the compound at pH 3 | 1 | assay format | Scientific Literature | |||
| 14. | ALA5098412 | A | Permeability of the compound at pH 6.8 | 1 | assay format | Scientific Literature | |||
| 15. | ALA5098413 | P | Kinetic solubility of compound at pH 6.8 by shake flask assay | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 16. | ALA5098414 | P | Kinetic solubility of compound at pH 1.5 by shake flask assay | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 17. | ALA5098415 | A | Efflux ratio of apparent permeability in human Caco-2 cells LC/MSMS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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