| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5137986 | B | PROTAC activity at CRBN/HDAC1 (unknown origin) by cell based assay | Homo sapiens | 1 | ALA5136981 | cell-based format | Scientific Literature | |
| 2. | ALA5137987 | B | PROTAC activity at CRBN/HDAC2 (unknown origin) by cell based assay | Homo sapiens | 1 | ALA5136981 | cell-based format | Scientific Literature | |
| 3. | ALA5137988 | B | PROTAC activity at CRBN/HDAC3 (unknown origin) by cell based assay | Homo sapiens | 1 | ALA5136981 | cell-based format | Scientific Literature | |
| 4. | ALA5137989 | B | PROTAC activity at CRBN/HDAC6 (unknown origin) by cell based assay | Homo sapiens | 1 | ALA5136981 | cell-based format | Scientific Literature | |
| 5. | ALA5154067 | B | Inhibition of recombinant full length C-terminal His/Flag-tagged human HDAC1 (1 to 482 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based microplate reader analysis | Homo sapiens | 11 | ALA5150069 | single protein format | Scientific Literature | |
| 6. | ALA5154068 | B | Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 (1 to 1215 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based microplate reader analysis | Homo sapiens | 11 | ALA5150069 | single protein format | Scientific Literature | |
| 7. | ALA5154069 | B | Selectivity index, ratio of IC50 for human HDAC1 to IC50 for human HDAC6 | Homo sapiens | 11 | ALA5150069 | assay format | Scientific Literature | |
| 8. | ALA5154070 | B | Induction of HDAC1 degradation in human HL-60 cells at 0.1 to 10 uM after 6 hrs by Western blot analysis | Homo sapiens | 3 | ALA5150069 | cell-based format | Scientific Literature | |
| 9. | ALA5154071 | B | Induction of HDAC6 degradation in human HL-60 cells at 0.1 to 10 uM after 6 hrs by Western blot analysis | Homo sapiens | 3 | ALA5150069 | cell-based format | Scientific Literature | |
| 10. | ALA5249950 | B | Inhibition of human HDAC1 | Homo sapiens | 1 | ALA5247611 | single protein format | Scientific Literature | |
| 11. | ALA5249951 | B | Inhibition of human HDAC2 | Homo sapiens | 1 | ALA5247611 | single protein format | Scientific Literature | |
| 12. | ALA5249952 | B | Inhibition of human HDAC3 | Homo sapiens | 1 | ALA5247611 | single protein format | Scientific Literature | |
| 13. | ALA5249953 | B | Inhibition of human HDAC6 | Homo sapiens | 1 | ALA5247611 | single protein format | Scientific Literature |
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