# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5124927 | Functional | Antiviral activity against HCMV AD-169 infected in HFF cells assessed as reduction in viral replication measured after 14 days | Human betaherpesvirus 5 | 7 | ALA5120909 | organism-based format | Scientific Literature | |
2. | ALA5124928 | Toxicity | Cytotoxicity against human HFF cells infected with HCMV AD-169 virus assessed as reduction in cell viability by cell titer-glo assay | Homo sapiens | 7 | ALA5120909 | cell-based format | Scientific Literature | |
3. | ALA5124929 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human HFF cells infected with HCMV AD-169 virus assessed as reduction in cell viability by cell titer-glo assay to EC50 for antiviral activity against HCMV AD-169 infected in HFF cells assessed as inhibition of virus-induced cytopathic effect measured after 14 days | 7 | ALA5120909 | cell-based format | Scientific Literature | ||
4. | ALA5124930 | Functional | Antiviral activity against VZV Ellen infected in HFF cells assessed as reduction in viral replication measured after 14 days | Human alphaherpesvirus 3 | 7 | ALA5120909 | organism-based format | Scientific Literature | |
5. | ALA5124931 | Toxicity | Cytotoxicity against human HFF cells infected with VZV Ellen virus assessed as reduction in cell viability by cell titer-glo assay | Homo sapiens | 7 | ALA5120909 | cell-based format | Scientific Literature | |
6. | ALA5124932 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human HFF cells infected with VZV Ellen virus assessed as reduction in cell viability by cell titer-glo assay to EC50 for antiviral activity against VZV Ellen infected in HFF cells assessed as inhibition of virus-induced cytopathic effect measured after 14 days | 7 | ALA5120909 | cell-based format | Scientific Literature | ||
7. | ALA5124933 | Functional | Anti-HIV activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 11 | ALA5120909 | organism-based format | Scientific Literature | |
8. | ALA5124934 | Functional | Anti-HIV activity against wild type HIV-2 ROD infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | Human immunodeficiency virus 2 | 11 | ALA5120909 | organism-based format | Scientific Literature | |
9. | ALA5124935 | Toxicity | Cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 11 | ALA5120909 | cell-based format | Scientific Literature | |
10. | ALA5124936 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for anti-HIV activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | 11 | ALA5120909 | cell-based format | Scientific Literature | ||
11. | ALA5124937 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for anti-HIV activity against wild type HIV-2 ROD infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | 11 | ALA5120909 | cell-based format | Scientific Literature | ||
12. | ALA5124938 | Functional | Antiviral activity against wild type HBV infected in human HepG2 2.2.15 cells assessed as reduction in viral replication pre incubated for 3 days followed by replacement with fresh compounds for another 3 days prior to pronase treatment by RT-qPCR analysis | Hepatitis B virus | 16 | ALA5120909 | organism-based format | Scientific Literature | |
13. | ALA5124940 | Functional | Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability by neutral red uptake assay | Homo sapiens | 6 | ALA5120909 | cell-based format | Scientific Literature |