| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5099988 | B | Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting method | Rattus norvegicus | 18 | cell membrane format | Scientific Literature | ||
| 2. | ALA5099989 | B | Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting method | Rattus norvegicus | 9 | cell membrane format | Scientific Literature | ||
| 3. | ALA5099990 | B | Displacement of [3H]HOCPCA from recombinant rat CaMK2alpha expressed in HEK293T cells measured after 1 hr by liquid scintillation counting method | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA5099991 | B | Potency index, ratio of Gamma hydroxy butyric acid Ki to test compound Ki for displacement of [3H]HOCPCA from recombinant rat CaMK2alpha expressed in HEK293T cells | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA5099992 | B | Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by surface plasmon resonance assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 6. | ALA5099993 | B | Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociation rate constant by surface plasmon resonance assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 7. | ALA5099996 | B | Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) expressed in Escherichia coli BL21 DE3 assessed as thermal stability by measuring change in melting temperature at 0.625 to 160 uM by SYPRO orange dye based differential scanning fluorimetry | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA5100000 | B | Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) Trp403 residue assessed as appearance of background fluorescence at 390 uM by Trp flip assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA5100001 | B | Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) Trp403 residue assessed as internal absorbance at high concentrations by Trp flip assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5100002 | B | Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) Trp403 residue assessed as inhibition of intrinsic tryptophan fluorescence by Trp flip assay | Homo sapiens | 2 | single protein format | Scientific Literature |
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