# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5106177 | B | Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhibition of PGE2 production after 30 mins by enzyme immuno-assay (EIA) | Mus musculus | 19 | cell-based format | Scientific Literature | ||
2. | ALA5106178 | B | Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA) | Mus musculus | 19 | cell-based format | Scientific Literature | ||
3. | ALA5106179 | B | Ratio IC50 for inhibition of COX1 in mouse J774 cells over inhibition of COX2 in mouse J774 cells | Mus musculus | 19 | cell-based format | Scientific Literature | ||
4. | ALA5106180 | A | Intrinsic clearance in human liver microsomes at 1 uM preincubated for 10 mins and measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
5. | ALA5106181 | A | Half-life in human liver microsomes at 1 uM preincubated for 10 mins and measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
6. | ALA5106182 | A | Intrinsic clearance in mouse liver microsomes at 1 uM preincubated for 10 mins and measured up to 60 mins by LC-MS/MS analysis | Mus musculus | 6 | microsome format | Scientific Literature | ||
7. | ALA5106183 | A | Half-life in mouse liver microsomes at 1 uM preincubated for 10 mins and measured up to 60 mins by LC-MS/MS analysis | Mus musculus | 6 | microsome format | Scientific Literature |