# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5122827 | B | Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substrate by fluorescence based analysis | Homo sapiens | 12 | assay format | Scientific Literature | ||
2. | ALA5122828 | B | Inhibition of recombinant human AKR1C2 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production at 100 uM using S-tetralol as substrate by fluorescence based analysis relative to control | Homo sapiens | 9 | assay format | Scientific Literature | ||
3. | ALA5122832 | P | Solubility of the compound in PBS at pH 7.4 incubated for 24 hrs by UHPLC analysis | 12 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5122833 | F | Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA5122836 | P | Lipophilicity, logD of the compound in n-octanol and phosphate buffer at pH 7.4 incubated for 4 hrs by UV-Vis spectrophotometer based shake flask method | 12 | small-molecule physicochemical format | Scientific Literature |