| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5129683 | B | Inhibition of human G9a (913 to 1193 residues) assessed as covalent modification by measuring G9a adduct formation at 50 uM incubated for 1 hr by mass spectrometry relative to control | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 2. | ALA5129684 | B | Inhibition of human G9a (913 to 1193 residues) using H3 peptide as substrate measured upto 45 mins in presence of SAM cofactor | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA5129685 | B | Inhibition of human GLP (982 to 1266 residues) using H3 peptide as substrate measured upto 45 mins in presence of SAM cofactor | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 4. | ALA5129686 | B | Binding affinity to human GLP (982 to 1266 residues) assessed as dissociation constant by isothermal titration calorimetry method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA5129687 | B | Binding affinity to human G9a (913 to 1193 residues) assessed as dissociation constant by isothermal titration calorimetry method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA5129690 | B | Inhibition of N-terminal GST-tagged human DOT1L (1 to 416 residues) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA5129691 | B | Inhibition of N-terminal His-tagged full-length recombinant human EZH1 ( 2 to 747 residues) expressed in baculovirus expression system at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA5129692 | B | Inhibition of N-terminal His-tagged EZH2 (2 to 746 residues) (unknown origin) expressed in baculovirus expression system at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA5129693 | B | Inhibition of N-terminal His-tagged MLL1 (3745 to 3969 residues) (unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA5129694 | B | Inhibition of N-terminal His-tagged NSD1 (1538 to 2696 residues) (unknown origin) expressed in baculovirus expression system at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA5129695 | B | Inhibition of NSD2 (2 to 1365 residues) (unknown origin) at 1 uM expressed in baculovirus expression system using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA5129696 | B | Inhibition of N-terminal GST tagged NSD3 (1021 to 1322 residues) (unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA5129697 | B | Inhibition of N-terminal GST tagged PRMT1 (2 to 371 residues) (unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA5129698 | B | Inhibition of N-terminal His-tagged PRMT3 (2 to 531 residues)(unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA5129699 | B | Inhibition of N-terminal GST-tagged PRMT4 (2 to 608 residues)(unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA5129700 | B | Inhibition of recombinant human N-terminal Flag-tagged PRMT5 (2 to 637 residues)/N-terminal His-tagged MEP50 (2 to 342 residues) expressed in baculovirus expression system at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA5129701 | B | Inhibition of N-terminal His-tagged full-length recombinant PRMT6 (2 to 375 residues) (unknown origin) expressed in baculovirus expression system at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA5129702 | B | Inhibition of N-terminal His-tagged full-length recombinant human PRMT7 (2 to 692 residues) expressed in baculovirus expression system at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA5129703 | B | Inhibition of N/C-terminal His-tagged PRMT8 (61 to 394 residues) (unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA5129704 | B | Inhibition of N-terminal GST-tagged SET1B (1629 to 1923 residues) (unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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