#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5161143	A	Drug concentration in STZ-induced diabetic peripheral neuropathic mechanical allodynia in overnight fasted Sprague-Dawley rat spinal cord at 1 mg/kg, po measured at 5.75 hrs post dose	Rattus norvegicus	3	ALA5154787	organism-based format	Scientific Literature
2.	ALA5161145	B	Inhibition of bacterially expressed GST-Xa-tagged human AAK1 using 5-FAM-labelled Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incubated for 3 hrs in presence of ATP by electrophoretic analysis	Homo sapiens	55	ALA5154787	single protein format	Scientific Literature
3.	ALA5161146	B	Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation counter analysis	Mus musculus	47	ALA5154787	tissue-based format	Scientific Literature
4.	ALA5161147	B	Inhibition of full length human AAK1 expressed in HEK293F cells assessed as suppression of AP2 phosphorylation measured after 3 hrs by Western blot analysis based cellular assay	Homo sapiens	39	ALA5154787	cell-based format	Scientific Literature
5.	ALA5161148	A	Metabolic stability in human liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	51	ALA5154787	microsome format	Scientific Literature
6.	ALA5161149	A	Metabolic stability in rat liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Rattus norvegicus	51	ALA5154787	microsome format	Scientific Literature
7.	ALA5161150	A	Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	51	ALA5154787	microsome format	Scientific Literature
8.	ALA5161151	A	Inhibition of CYP3A4 (unknown origin) incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	48	ALA5154787	single protein format	Scientific Literature
9.	ALA5161152	A	Volume of distribution at steady state in rat at 3 mg/kg,po or 2 mg/kg,iv	Rattus norvegicus	3	ALA5154787	organism-based format	Scientific Literature
10.	ALA5161153	A	Efflux ratio of permeability in human Caco-2 cells	Homo sapiens	6	ALA5154787	cell-based format	Scientific Literature
11.	ALA5161166	A	Half life in rat at 3 mg/kg, po or 2 mg/kg, iv	Rattus norvegicus	3	ALA5154787	organism-based format	Scientific Literature
12.	ALA5161167	A	Total body clearance in rat at 3 mg/kg, po or 2 mg/kg, iv	Rattus norvegicus	3	ALA5154787	organism-based format	Scientific Literature
13.	ALA5161168	P	Chemical stability of the compound assessed as remaining product at pH 7.4 measured after 22 hrs		1	ALA5154787	small-molecule physicochemical format	Scientific Literature
14.	ALA5161169	A	Oral bioavailability in rat at 3 mg/kg or 2 mg/kg,iv	Rattus norvegicus	3	ALA5154787	organism-based format	Scientific Literature
15.	ALA5161170	P	Chemical stability of the compound assessed as remaining product at pH 1 measured after 22 hrs		1	ALA5154787	small-molecule physicochemical format	Scientific Literature
16.	ALA5161171	T	Genotoxicity in Salmonella typhimurium by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	2	ALA5154787	assay format	Scientific Literature
17.	ALA5161172	T	Genotoxicity in chinese hamster CHO cells in presence of metabolic activation system at 169 uM by IVMN assay	Cricetulus griseus	1	ALA5154787	cell-based format	Scientific Literature
18.	ALA5161173	T	Genotoxicity in chinese hamster CHO cells without metabolic activation system at 59 uM by IVMN assay	Cricetulus griseus	1	ALA5154787	cell-based format	Scientific Literature
19.	ALA5161174	P	Solubility of compound at pH 1 measured after 24 hrs		1	ALA5154787	small-molecule physicochemical format	Scientific Literature
20.	ALA5161175	P	Solubility of compound at pH 2 measured after 24 hrs		1	ALA5154787	small-molecule physicochemical format	Scientific Literature