# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5136494 | A | Clearance in CD-1 mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
2. | ALA5136495 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic T124/T125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
3. | ALA5136496 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic N124/A125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 13 | organism-based format | Scientific Literature | ||
4. | ALA5136497 | T | Cytotoxicity against human MT2 cells | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
5. | ALA5136499 | A | Clearance in cynomolgus monkey at 1 mg/kg, iv by LC-MS/MS analysis | Macaca fascicularis | 2 | organism-based format | Scientific Literature | ||
6. | ALA5136501 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
7. | ALA5136502 | A | AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
8. | ALA5136503 | A | Oral bioavailability in Sprague-Dawley rat at 5 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
9. | ALA5136504 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic A124/T125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
10. | ALA5136505 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic T124/A125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
11. | ALA5136506 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic N124/T125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
12. | ALA5136507 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic A124/A125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
13. | ALA5136508 | F | Antiviral activity against recombinant HIV1 NLRep-Rluc harbouring polymorphic T124/V125 integrase infected in human MT-2 cells assessed as inhibition of virus growth in presence of fetal bovine serum by measuring luciferase activity after 4 days | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
14. | ALA5136509 | A | AUC (0 to infinity) in CD-1 mouse at 5 mg/kg, po by LC-MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA5136510 | A | Oral bioavailability in CD-1 mouse at 5 mg/kg by LC-MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA5136511 | A | Clearance in Beagle dog at 1 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
17. | ALA5136512 | A | AUC (0 to infinity) in Beagle dog at 2 mg/kg, po by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
18. | ALA5136513 | A | Oral bioavailability in Beagle dog at 2 mg/kg by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
19. | ALA5136514 | A | AUC (0 to infinity) in cynomolgus monkey at 2 mg/kg, po by LC-MS/MS analysis | Macaca fascicularis | 2 | organism-based format | Scientific Literature | ||
20. | ALA5136515 | A | Oral bioavailability in cynomolgus monkey at 2 mg/kg by LC-MS/MS analysis | Macaca fascicularis | 2 | organism-based format | Scientific Literature |