# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5129156 | F | Antiangiogenic activity in HUVEC cells assessed as inhibition of VEGF-induced cell proliferation at 20 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 52 | ALA5126581 | cell-based format | Scientific Literature | |
2. | ALA5129157 | B | Inhibition of VEGFR2 phosphorylation in VEGF-induced HUVEC cells assessed as reduction in pVEGFR2 level at 20 uM incubated for 5 mins by Western blot analysis | Homo sapiens | 6 | ALA5126581 | cell-based format | Scientific Literature | |
3. | ALA5129162 | B | Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] (4:1) as substrate at 20 uM incubated for 45 mins by kinase-glo max reagent based luminescence analysis relative to control | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
4. | ALA5129163 | B | Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] (4:1) as substrate at 10 uM incubated for 45 mins by kinase-glo max reagent based luminescence analysis | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
5. | ALA5129164 | B | Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] (4:1) as substrate incubated for 45 mins by kinase-glo max reagent based luminescence analysis | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
6. | ALA5129165 | B | Inhibition of TNK2 (unknown origin) assessed as residual activity at 10 uM incubated for 1 hr by KinomeScan analysis relative to control | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
7. | ALA5129166 | B | Inhibition of PRKD2 (unknown origin) assessed as residual activity at 10 uM incubated for 1 hr by KinomeScan analysis relative to control | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
8. | ALA5129167 | B | Inhibition of MYLK4 (unknown origin) assessed as residual activity at 10 uM incubated for 1 hr by KinomeScan analysis relative to control | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
9. | ALA5129168 | B | Inhibition of c-KIT (unknown origin) assessed as residual activity at 10 uM incubated for 1 hr by KinomeScan analysis relative to control | Homo sapiens | 1 | ALA5126581 | single protein format | Scientific Literature | |
10. | ALA5129169 | F | Cytotoxicity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 21 | ALA5126581 | cell-based format | Scientific Literature | |
11. | ALA5129170 | T | Cytotoxicity against HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 21 | ALA5126581 | cell-based format | Scientific Literature | |
12. | ALA5129171 | T | Selectivity index, ratio of IC50 for cytotoxicity against HEK293 cells to IC50 for cytotoxicity against human MDA-MB-468 cells | Homo sapiens | 21 | ALA5126581 | cell-based format | Scientific Literature |