# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5144917 | Binding | Inhibition of PIP5Kalpha (unknown origin) | Homo sapiens | 4 | ALA5143552 | single protein format | Scientific Literature | |
2. | ALA5144918 | Binding | Inhibition of PIP5Kbeta (unknown origin) | Homo sapiens | 4 | ALA5143552 | single protein format | Scientific Literature | |
3. | ALA5144919 | Binding | Inhibition of PIP5Kgamma (unknown origin) | Homo sapiens | 32 | ALA5143552 | single protein format | Scientific Literature | |
4. | ALA5144920 | Binding | Inhibition of PI3Kalpha (unknown origin) | Homo sapiens | 31 | ALA5143552 | single protein format | Scientific Literature | |
5. | ALA5144923 | Physicochemical | Lipophilicity, logD of compound at pH 7.4 by shake flask method | 31 | ALA5143552 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA5144924 | Physicochemical | Thermodynamic aqueous solubility at pH 7.4 | 30 | ALA5143552 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA5144925 | Binding | Inhibition of PI3Kbeta (unknown origin) | Homo sapiens | 3 | ALA5143552 | single protein format | Scientific Literature | |
8. | ALA5144926 | Binding | Inhibition of PI3Kgamma (unknown origin) | Homo sapiens | 3 | ALA5143552 | single protein format | Scientific Literature | |
9. | ALA5144927 | Binding | Inhibition of PI3Kdelta (unknown origin) | Homo sapiens | 3 | ALA5143552 | single protein format | Scientific Literature | |
10. | ALA5144928 | Binding | Inhibition of PI4Kalpha (unknown origin) | Homo sapiens | 3 | ALA5143552 | single protein format | Scientific Literature | |
11. | ALA5144929 | Binding | Inhibition of PI4Kbeta (unknown origin) | Homo sapiens | 3 | ALA5143552 | single protein format | Scientific Literature | |
12. | ALA5144930 | Binding | Inhibition of PDGFRbeta (unknown origin) | Homo sapiens | 3 | ALA5143552 | single protein format | Scientific Literature | |
13. | ALA5144931 | Functional | Inhibition of IP1 synthesis in mouse NIH3T3 cells over expressing PDGFRbeta stimulated with PDGF | Mus musculus | 3 | ALA5143552 | cell-based format | Scientific Literature | |
14. | ALA5144932 | Binding | Inhibition of PDK1 in human BT-474 cells assessed as reduction in AKT phosphorylation at T308 residue incubated for 2 hrs | Homo sapiens | 3 | ALA5143552 | cell-based format | Scientific Literature | |
15. | ALA5144934 | ADME | Intrinsic clearance in rat hepatocytes assessed per 10^6 cells | Rattus norvegicus | 3 | ALA5143552 | cell-based format | Scientific Literature | |
16. | ALA5144935 | ADME | Intrinsic clearance in human liver microsome | Homo sapiens | 3 | ALA5143552 | microsome format | Scientific Literature | |
17. | ALA5144937 | ADME | Efflux ratio of permeability across basolateral to apical membrane to apical to basolateral membrane in human Caco2 cells | Homo sapiens | 5 | ALA5143552 | cell-based format | Scientific Literature |