| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5159504 | B | Inhibition of PDE10A2 (449 to 770 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 2. | ALA5159505 | B | Inhibition of PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 3. | ALA5159506 | B | Inhibition of PDE5A1 (535 to 860 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 4. | ALA5159507 | A | Stability in human liver microsomes assessed as half life measure upto 45 mins in presence of NADPH by LC-MS analysis | Homo sapiens | 1 | ALA5154753 | microsome format | Scientific Literature | |
| 5. | ALA5159510 | B | Inhibition of PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 26 | ALA5154753 | assay format | Scientific Literature | |
| 6. | ALA5159511 | B | Inhibition of PDE4B2 (152 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 7. | ALA5159512 | B | Inhibition of PDE1B (10 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 8. | ALA5159513 | B | Inhibition of PDE2A (580 to 919 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 9. | ALA5159514 | B | Inhibition of PDE3A (679 to 1087 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 10. | ALA5159515 | B | Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 11. | ALA5159516 | B | Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 12. | ALA5159517 | B | Selectivity ratio of IC50 for PDE4B2 (152 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 13. | ALA5159518 | B | Selectivity ratio of IC50 for PDE1B (10 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 14. | ALA5159519 | B | Selectivity ratio of IC50 for PDE2A (580 to 919 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 15. | ALA5159520 | B | Selectivity ratio of IC50 for PDE3A (679 to 1087 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 16. | ALA5159521 | B | Selectivity ratio of IC50 for PDE5A1 (535 to 860 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 17. | ALA5159522 | B | Selectivity ratio of IC50 for PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 18. | ALA5159523 | B | Selectivity ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 19. | ALA5159524 | B | Selectivity ratio of IC50 for PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature | |
| 20. | ALA5159525 | B | Selectivity ratio of IC50 for PDE10A2 (449 to 770 residues) (unknown origin) expressed in Escherichia coli BL21 to IC50 for PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 | Homo sapiens | 1 | ALA5154753 | assay format | Scientific Literature |
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