# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5142410 | F | Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 80 | ALA5137091 | cell membrane format | Scientific Literature | |
2. | ALA5142414 | F | Antagonist activity at human FFAR2 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of C3 fatty acid propionate-induced [35S]GTPgammaS binding at 10 uM preincubated for 15 mins followed by C3 fatty acid propionate addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 4 | ALA5137091 | cell membrane format | Scientific Literature | |
3. | ALA5142415 | F | Antagonist activity at human FFAR3 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of C3 fatty acid propionate-induced [35S]GTPgammaS binding at 10 uM preincubated for 15 mins followed by C3 fatty acid propionate addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 4 | ALA5137091 | cell membrane format | Scientific Literature | |
4. | ALA5142416 | P | Distribution coefficient, log D of compound at pH 7.4 | 5 | ALA5137091 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA5142417 | P | Kinetic solubility of compound | 5 | ALA5137091 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA5142418 | A | Half life in mouse hepatocytes | Mus musculus | 5 | ALA5137091 | cell-based format | Scientific Literature | |
7. | ALA5142419 | A | Half life in human liver microsomes | Homo sapiens | 5 | ALA5137091 | microsome format | Scientific Literature | |
8. | ALA5142420 | A | Protein binding in mouse plasma assessed as unbound fraction | Mus musculus | 5 | ALA5137091 | cell-free format | Scientific Literature |