#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5157310	B	Agonist activity at FXR-LBD (unknown origin) assessed as induction of coactivator SRC-1 peptide recruitment measured by TR-FRET assay	Homo sapiens	16	ALA5154690	single protein format	Scientific Literature
2.	ALA5157311	B	Agonist activity at FXR-LBD (unknown origin) assessed as induction of coactivator SRC-1 peptide recruitment measured by TR-FRET assay in relative to GW4064	Homo sapiens	15	ALA5154690	single protein format	Scientific Literature
3.	ALA5157312	B	Agonist activity at human FXR expressed in HEK293T cells by luciferase reporter assay	Homo sapiens	16	ALA5154690	cell-based format	Scientific Literature
4.	ALA5157313	B	Agonist activity at human FXR expressed in HEK293T cells by luciferase reporter assay in relative to GW4064	Homo sapiens	15	ALA5154690	cell-based format	Scientific Literature
5.	ALA5157316	A	Half-life in male Sprague-Dawley rat at 5 mg/kg, po measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
6.	ALA5157317	A	Cmax in male Sprague-Dawley rat at 5 mg/kg, po measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
7.	ALA5157318	A	AUC (0 to t) in male Sprague-Dawley rat at 5 mg/kg, po measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
8.	ALA5157319	A	AUC (0 to t) in male Sprague-Dawley rat at 1 mg/kg, iv measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
9.	ALA5157320	A	Clearance in male Sprague-Dawley rat at 1 mg/kg, iv measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
10.	ALA5157321	A	Volume of distribution at steady state in male Sprague-Dawley rat at 1 mg/kg, iv measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
11.	ALA5157322	A	Oral bioavailability in male Sprague-Dawley rat at 5 mg/kg measured by LC-MS/MS analysis	Rattus norvegicus	4	ALA5154690	organism-based format	Scientific Literature
12.	ALA5157323	F	Anti-NASH activity against high fat (HF) diet-induced nonalcoholic steatohepatitis in leptin-deficient ob/ob mouse model assessed as reduction in serum ALT level at 3 mg/kg, po administered once daily from week 5 to 10	Mus musculus	4	ALA5154690	organism-based format	Scientific Literature
13.	ALA5157324	F	Anti-NASH activity against high fat (HF) diet-induced nonalcoholic steatohepatitis in leptin-deficient ob/ob mouse model assessed as reduction in serum TG level at 3 mg/kg, po administered once daily from week 5 to 10	Mus musculus	4	ALA5154690	organism-based format	Scientific Literature
14.	ALA5157325	F	Anti-NASH activity against high fat (HF) diet-induced nonalcoholic steatohepatitis in leptin-deficient ob/ob mouse model assessed as reduction in liver cholesterol level at 3 mg/kg, po administered once daily from week 5 to 10	Mus musculus	4	ALA5154690	organism-based format	Scientific Literature
15.	ALA5157326	F	Anti-NASH activity against high fat (HF) diet-induced nonalcoholic steatohepatitis in leptin-deficient ob/ob mouse model assessed as reduction in NASH activity score (NAS) at 3 mg/kg, po administered once daily from week 5 to 10	Mus musculus	1	ALA5154690	organism-based format	Scientific Literature
16.	ALA5157327	F	Agonist activity in human GPBAR1 assessed as increase in intracellular cAMP level	Homo sapiens	1	ALA5154690	cell-based format	Scientific Literature
17.	ALA5157328	F	Agonist activity in human GPBAR1 assessed as increase in intracellular cAMP level relative to control	Homo sapiens	1	ALA5154690	cell-based format	Scientific Literature
18.	ALA5157329	B	Agonist activity at estrogen receptor alpha (unknown origin)	Homo sapiens	1	ALA5154690	single protein format	Scientific Literature
19.	ALA5157330	B	Agonist activity at estrogen receptor beta (unknown origin)	Homo sapiens	1	ALA5154690	single protein format	Scientific Literature
20.	ALA5157331	B	Agonist activity at PPARalpha (unknown origin)	Homo sapiens	1	ALA5154690	single protein format	Scientific Literature