# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5157583 | B | Inhibition of KRAS G12C mutant (unknown origin) assessed as inhibition of SOS1-catalyzed nucleotide exchange measured by HTRF assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA5157584 | F | Antiproliferative activity against human NCI-H358 cells harboring KRAS G12C mutant measured after 72 hrs by CCK-8 assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA5157585 | F | Antiproliferative activity against human NCI-H23 cells harboring KRAS G12C mutant measured after 72 hrs by CCK-8 assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA5157586 | F | Antiproliferative activity against human A549 cells harboring KRAS G12S mutant measured after 72 hrs by CCK-8 assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA5157587 | B | Reversible covalent binding affinity to KRAS G12C mutant (unknown origin) incubated for 2 hrs and measured by MALDI-TOF-MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature |