# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5100223 | B | Inhibition of N-terminal His/SUMO tagged wild type human c-Met (1038 to 1346 residues) transfected in Escherichia coli using Tyr06 peptide as substrate incubated for 1 hr in presence of ATP by FRET-based Z'-Lyte assay | Homo sapiens | 51 | assay format | Scientific Literature | ||
2. | ALA5100224 | F | Antiproliferative activity against human Hs746T cells harboring MET alterations assessed as inhibition of cell proliferation incubated for 5 days by CCK8 assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
3. | ALA5100225 | F | Potency index, ratio of test compound IC50 to tepotinib IC50 for antiproliferative activity against human Hs746T cells harboring MET alterations assessed as inhibition of cell proliferation incubated for 5 days by CCK8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature |