# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5157625 | B | Inhibition of PHD2 (unknown origin) at 0.5 uM measured by fluorescence polarization assay relative to control | Homo sapiens | 34 | single protein format | Scientific Literature | ||
2. | ALA5157626 | B | Inhibition of PHD2 (unknown origin) at 1 uM measured by fluorescence polarization assay relative to control | Homo sapiens | 34 | single protein format | Scientific Literature | ||
3. | ALA5157627 | B | Inhibition of PHD2 (unknown origin) at 10 uM measured by fluorescence polarization assay relative to control | Homo sapiens | 34 | single protein format | Scientific Literature | ||
4. | ALA5157628 | B | Inhibition of HDAC in human HK-2 cells assessed as increase in histone H3 expression acetylation at 5 uM measured by western blot analysis | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
5. | ALA5157629 | B | Inhibition of PHD2 (unknown origin) measured by fluorescence polarization assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
6. | ALA5157630 | B | Inhibition of HDAC1 (unknown origin) using trypsin and Ac-peptide as substrates | Homo sapiens | 2 | single protein format | Scientific Literature | ||
7. | ALA5157631 | B | Inhibition of HDAC2 (unknown origin) using trypsin and Ac-peptide as substrates | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA5157632 | B | Inhibition of HDAC4 (unknown origin) using trypsin and Ac-peptide as substrates | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA5157633 | B | Inhibition of HDAC6 (unknown origin) using trypsin and Ac-peptide as substrates | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA5157634 | F | Antiproliferative activity against human MCF7 cells assessed as decrease in cell viability at 50 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5157635 | F | Antiproliferative activity against human A549 cells assessed as decrease in cell viability at 50 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5157636 | F | Antiproliferative activity against human MCF7 cells assessed as decrease in cell viability at 50 uM in presence of 100 uM cisplatin relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5157637 | F | Antiproliferative activity against human A549 cells assessed as decrease in cell viability at 50 uM in presence of 40 uM cisplatin relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5157638 | F | Induction of apoptosis in human MCF7 cells assessed as apoptotic cell population at 50 uM measured by Annexin V-FITC/propidium iodide staining based flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5157639 | F | Induction of apoptosis in human A549 cells assessed as apoptotic cell population at 50 uM measured by Annexin V-FITC/propidium iodide staining based flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA5157640 | F | Induction of apoptosis in human MCF7 cells assessed as apoptotic cell population at 50 uM in presence of 100 uM cisplatin measured by Annexin V-FITC/propidium iodide staining based flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA5157641 | F | Induction of apoptosis in human A549 cells assessed as apoptotic cell population at 50 uM in presence of 100 uM cisplatin measured by Annexin V-FITC/propidium iodide staining based flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA5157642 | F | Antiproliferative activity against human HK-2 cells assessed as decrease in cell viability at 100 uM measured after 24 hrs by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA5157644 | F | Antiproliferative activity against human HK-2 cells assessed as decrease in cell viability at 50 uM measured in presence of 10 uM cisplatin after 24 hrs by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA5157645 | F | Nephroprotective activity against cisplatin-induced acute kidney injury in male C57BL/6 mouse assessed as plasma BUN concentration at 10 mg/kg/day, ip | Mus musculus | 3 | organism-based format | Scientific Literature |