# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5129358 | B | Binding affinity to immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in retention time by chromatographic analysis | Homo sapiens | 1 | ALA5126591 | assay format | Scientific Literature | |
2. | ALA5159993 | F | Anti-asthmatic activity against ovalbumin-induced asthmatic mouse model assessed as decrease in IgE level in serum administered orally once daily for 7 days by ELISA | Mus musculus | 1 | ALA5154767 | organism-based format | Scientific Literature | |
3. | ALA5159994 | F | Anti-asthmatic activity against ovalbumin-induced asthmatic mouse model assessed as decrease in IL-13 level in BALF administered orally once daily for 7 days by ELISA | Mus musculus | 1 | ALA5154767 | organism-based format | Scientific Literature | |
4. | ALA5159998 | F | Anti-asthmatic activity against ovalbumin-induced asthmatic mouse model assessed as infiltration of inflammatory cells in the perivascular and peribronchiolar region of lungs at 10 to 20 mg/kg, po administered once daily for 7 days by H and E staining based light microscopic analysis | Mus musculus | 1 | ALA5154767 | organism-based format | Scientific Literature | |
5. | ALA5160007 | F | Anti-asthmatic activity against ovalbumin-induced asthmatic mouse model assessed as decrease in IL-4 level in BALF administered orally once daily for 7 days by ELISA | Mus musculus | 1 | ALA5154767 | organism-based format | Scientific Literature | |
6. | ALA5160008 | F | Anti-asthmatic activity against ovalbumin-induced asthmatic mouse model assessed as decrease in IL-5 level in BALF at 10 mg/kg, po administered once daily for 7 days by ELISA | Mus musculus | 1 | ALA5154767 | organism-based format | Scientific Literature | |
7. | ALA5160011 | F | Increase in beta2 adrenoceptor expression in bronchus in ovalbumin-induced asthmatic mouse model administered orally once daily for 7 days by Western blot analysis | Mus musculus | 1 | ALA5154767 | assay format | Scientific Literature | |
8. | ALA5160012 | F | Decrease in CysLT receptor expression in bronchus in ovalbumin-induced asthmatic mouse model administered orally once daily for 7 days by Western blot analysis | Mus musculus | 1 | ALA5154767 | assay format | Scientific Literature | |
9. | ALA5160015 | B | Binding affinity to immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3) by receptor chromatography | Homo sapiens | 2 | ALA5154767 | assay format | Scientific Literature | |
10. | ALA5160016 | B | Binding affinity to immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate constant by receptor chromatography | Homo sapiens | 2 | ALA5154767 | assay format | Scientific Literature | |
11. | ALA5160017 | B | Binding affinity to immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as association rate constant by receptor chromatography | Homo sapiens | 2 | ALA5154767 | assay format | Scientific Literature | |
12. | ALA5160018 | B | Binding affinity to immobilized Halo tag-fused CysLT receptor (unknown origin) expressed in Escherichia coli BL21 (DE3) by receptor chromatography | Homo sapiens | 2 | ALA5154767 | assay format | Scientific Literature | |
13. | ALA5160019 | B | Binding affinity to immobilized Halo tag-fused CysLT receptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate constant by receptor chromatography | Homo sapiens | 2 | ALA5154767 | assay format | Scientific Literature | |
14. | ALA5160020 | B | Binding affinity to immobilized Halo tag-fused CysLT receptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as association rate constant by receptor chromatography | Homo sapiens | 2 | ALA5154767 | assay format | Scientific Literature |