#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5122827	B	Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substrate by fluorescence based analysis	Homo sapiens	12	ALA5120830	assay format	Scientific Literature
2.	ALA5122828	B	Inhibition of recombinant human AKR1C2 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production at 100 uM using S-tetralol as substrate by fluorescence based analysis relative to control	Homo sapiens	9	ALA5120830	assay format	Scientific Literature
3.	ALA5122831	B	Selectivity index, ratio of inhibition of recombinant human AKR1C2 transfected in Escherichia coli BL21 (DE) to IC50 for inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE)	Homo sapiens	3	ALA5120830	assay format	Scientific Literature
4.	ALA5122832	P	Solubility of the compound in PBS at pH 7.4 incubated for 24 hrs by UHPLC analysis		12	ALA5120830	small-molecule physicochemical format	Scientific Literature
5.	ALA5122833	F	Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as inhibition of cell growth incubated for 72 hrs by SRB assay	Homo sapiens	12	ALA5120830	cell-based format	Scientific Literature
6.	ALA5122836	P	Lipophilicity, logD of the compound in n-octanol and phosphate buffer at pH 7.4 incubated for 4 hrs by UV-Vis spectrophotometer based shake flask method		12	ALA5120830	small-molecule physicochemical format	Scientific Literature
7.	ALA5122838	F	Inhibition of prostate specific antigen expression in human 22Rv1 cells expressing AKR1C3 at 5 to 50 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	2	ALA5120830	cell-based format	Scientific Literature
8.	ALA5122839	F	Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as reduction in cell viability at 40 to 60 uM incubated for 72 hrs in presence of abiraterone by SRB assay relative to either drug alone	Homo sapiens	2	ALA5120830	cell-based format	Scientific Literature
9.	ALA5122840	F	Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as reduction in cell viability at 40 to 60 uM incubated for 72 hrs in presence of , enzalutamide by SRB assay relative to either drug alone	Homo sapiens	2	ALA5120830	cell-based format	Scientific Literature