# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5137203 | B | Displacement of [125I]-Tyr-SRIF 14 from human SST2A receptor expressed in membrane measured after 90 mins by gamma counting analysis | Homo sapiens | 59 | ALA5136959 | cell membrane format | Scientific Literature | |
2. | ALA5137204 | F | Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured after 2.5 to 20 hrs in presence of 3-isobutyl-1-methylxanthine by TR-FRET LANCE assay | Homo sapiens | 54 | ALA5136959 | cell-based format | Scientific Literature | |
3. | ALA5137205 | B | Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysis | Homo sapiens | 59 | ALA5136959 | cell membrane format | Scientific Literature | |
4. | ALA5137206 | B | Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis | Homo sapiens | 34 | ALA5136959 | cell membrane format | Scientific Literature | |
5. | ALA5137207 | B | Displacement of [125I]-Tyr-SRIF 14 from SST3 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis | Homo sapiens | 33 | ALA5136959 | cell membrane format | Scientific Literature | |
6. | ALA5137208 | B | Displacement of [125I]-Tyr-SRIF 14 from SST5 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis | Homo sapiens | 33 | ALA5136959 | cell membrane format | Scientific Literature | |
7. | ALA5137209 | B | Selectivity ratio of Ki for displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane to Ki for displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane | Homo sapiens | 2 | ALA5136959 | assay format | Scientific Literature | |
8. | ALA5137210 | B | Selectivity ratio of Ki for displacement of [125I]-Tyr-SRIF 14 from human SST2A receptor expressed in membrane to Ki for displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane | Homo sapiens | 1 | ALA5136959 | assay format | Scientific Literature | |
9. | ALA5137211 | B | Selectivity ratio of Ki for displacement of [125I]-Tyr-SRIF 14 from SST3 receptor (unknown origin) expressed in membrane to Ki for displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane | Homo sapiens | 1 | ALA5136959 | assay format | Scientific Literature | |
10. | ALA5137212 | B | Selectivity ratio of Ki for displacement of [125I]-Tyr-SRIF 14 from SST5 receptor (unknown origin) expressed in membrane to Ki for displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane | Homo sapiens | 1 | ALA5136959 | assay format | Scientific Literature | |
11. | ALA5137213 | A | Efflux ratio of permeability across basolateral to apical side over apical to basolateral side in MDCK-MDR1 cells at 10 uM measured after 2 hrs by LC-MS/MS analysis | Canis lupus familiaris | 5 | ALA5136959 | cell-based format | Scientific Literature | |
12. | ALA5137214 | F | Antialzheimer activity in SAMP8 mouse model of AD-related cognitive deficit assessed as improvement in acquisition learning at 1 mg/kg, ip administered once daily for 21 days by T-maze test | Mus musculus | 1 | ALA5136959 | organism-based format | Scientific Literature | |
13. | ALA5137215 | F | Antialzheimer activity in SAMP8 mouse model of AD-related cognitive deficit assessed as increase in memory retention at 0.01 to 1 mg/kg, ip administered once daily for 28 days by T-maze test | Mus musculus | 1 | ALA5136959 | organism-based format | Scientific Literature | |
14. | ALA5137216 | F | Antialzheimer activity in SAMP8 mouse model of AD-related cognitive deficit assessed as increase in memory retention at 0.01 to 10 mg/kg, po administered once daily for 28 days by T-maze test | Mus musculus | 1 | ALA5136959 | organism-based format | Scientific Literature |