| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5147904 | B | Positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-induced response in presence of GABA by FLIPR assay | Homo sapiens | 6 | ALA5143681 | cell-based format | Scientific Literature | |
| 2. | ALA5147908 | B | Positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-induced response at 5 uM in presence of flumazenil by FLIPR assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 3. | ALA5147909 | B | Additive positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-induced response at 0.5 to 8 uM in presence of diazepam by FLIPR assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 4. | ALA5147910 | B | Additive positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-induced response at 0.5 to 8 uM in presence of etazolate by FLIPR assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 5. | ALA5147911 | B | Positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-induced response at 10 uM in presence of pregnenolone sulfate by FLIPR assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 6. | ALA5147912 | B | Additive positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-induced response at 0.5 to 4 uM in presence of allopregnanolone by FLIPR assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 7. | ALA5147913 | B | Positive allosteric modulation of recombinant GABAA alpha1beta2gamma2 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at -70 mV holding potential in presence of GABA EC3 to 7 by two-microelectrode voltage-clamp assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 8. | ALA5147914 | B | Positive allosteric modulation of recombinant GABAA alpha1beta2gamma2 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at -70 mV holding potential in presence of GABA EC3 to 7 by two-microelectrode voltage-clamp assay relative to control | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 9. | ALA5147915 | B | Positive allosteric modulation of recombinant GABAA alpha1beta2 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at -70 mV holding potential in presence of GABA EC3 to 7 by two-microelectrode voltage-clamp assay | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature | |
| 10. | ALA5147916 | B | Positive allosteric modulation of recombinant GABAA alpha1beta2 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at -70 mV holding potential in presence of GABA EC3 to 7 by two-microelectrode voltage-clamp assay relative to control | Homo sapiens | 1 | ALA5143681 | cell-based format | Scientific Literature |
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