# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5160484 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
2. | ALA5160485 | F | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
3. | ALA5160486 | F | Antiproliferative activity against human U2OS cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
4. | ALA5160487 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
5. | ALA5160488 | F | Induction of apoptosis in human A549 cells assessed as downregulation of p-Akt level incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5160489 | F | Induction of apoptosis in human A549 cells assessed as downregulation of Cdk4 level incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5160490 | F | Upregulation of Bax protein expression in human A549 cells at 1.25 to 5 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA5160491 | F | Upregulation of Bcl-2 protein expression in human A549 cells at 1.25 to 5 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5160492 | F | Upregulation of cleaved capase-3 expression in human A549 cells at 1.25 to 5 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5160493 | F | Upregulation of cleaved PARP expression in human A549 cells at 1.25 to 5 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5160494 | F | Induction of apoptosis in human A549 cells assessed as total apoptotic cells at 0.2 uM incubated for 48 hrs Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5160495 | F | Induction of apoptosis in human A549 cells assessed as total apoptotic cells at 0.4 uM incubated for 48 hrs Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5160496 | F | Induction of apoptosis in human A549 cells assessed as total apoptotic cells at 0.8 uM incubated for 48 hrs Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5160497 | F | Induction of apoptosis in human A549 cells at 0.1 to 0.4 uM incubated for 48 hrs by Hoechst33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5160498 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation of cells at G0/G1 phase measured after 24 hrs by PI staining based flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA5160499 | F | Antiproliferative activity against human A549 cells expressing Hsp90-Cdc37 protein assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA5160500 | F | Antiproliferative activity against human A549 cells expressing Hsp90 protein assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA5160501 | F | Antiproliferative activity against human A549 cells expressing Cdc37 protein assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA5160502 | F | Antitumor activity against human A549 cells xenografted in BALB/c mouse lung tumor model assessed as tumor weight at 1 mg/kg, ip measured every day for 21 days by caliper method | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
20. | ALA5160503 | F | Antitumor activity against human A549 cells xenografted in BALB/c mouse lung tumor model assessed as tumor inhibition rate at 1 mg/kg, ip measured every day for 21 days by caliper method relative to control | Homo sapiens | 2 | organism-based format | Scientific Literature |