#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5163566	F	Ex vivo receptor occupancy at V2R in isolated perfused Sprague-Dawley rat kidney assessed as dissociation half life at 0.1 uM incubated for 30 mins by LC-MS analysis	Rattus norvegicus	2	ALA5154831	tissue-based format	Scientific Literature
2.	ALA5163568	F	Suppression of renal cyst development in embryonic kidney of 8-Br-cAMP induced C57BL/6 mouse mouse model of autosomal dominant polycystic kidney disease assessed as residence time dependent measured after 8 days	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
3.	ALA5163569	B	Displacement of conivaptan-red from SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition constant measured after 2 hrs by HTRF assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
4.	ALA5163570	B	Inhibition of conivaptan-red binding to SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as binding constant (Kon) measured after 2 hrs by HTRF competitive binding assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
5.	ALA5163571	B	Inhibition of conivaptan-red binding to SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as binding constant (Koff) measured after 2 hrs by HTRF competitive binding assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
6.	ALA5163572	B	Inhibition of conivaptan-red binding to SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as residence time (1/koff) measured after 2 hrs by HTRF competitive binding assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
7.	ALA5163573	F	Antagonist activity at human V2 receptor expressed in CHO cells assessed as reduction in vasopressin induced cAMP production preincubated for 30 mins followed by vasopressin stimulation and measured after 30 mins	Homo sapiens	3	ALA5154831	cell-based format	Scientific Literature
8.	ALA5163574	F	Insurmountable antagonist activity at human V2 receptor expressed in CHO cells assessed as decrease in maximal response preincubated for 30 mins followed by vasopressin stimulation and measured after 30 mins	Homo sapiens	2	ALA5154831	cell-based format	Scientific Literature
9.	ALA5163575	F	Antagonist activity at human V2 receptor expressed in CHO cells assessed as recovery of cAMP production preincubated for 30 mins followed by compound washout and subsequent vasopressin stimulation for 30 mins and measured after 1 hr	Homo sapiens	3	ALA5154831	cell-based format	Scientific Literature
10.	ALA5163576	F	Antagonist activity at human V2 receptor expressed in CHO cells assessed as assessed as target occupancy preincubated for 30 mins followed by vasopressin stimulation for 30 mins	Homo sapiens	2	ALA5154831	cell-based format	Scientific Literature
11.	ALA5163578	F	Suppression of renal cyst development in embryonic kidney of 8-Br-cAMP induced C57BL/6 mouse mouse model of autosomal dominant polycystic kidney disease measured after 8 days	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
12.	ALA5163579	F	Invivo antagonist activity at V2R in Pkd1 knockout mouse model of autosomal dominant polycystic kidney disease assessed as reduction in kidney size at 2 mg/kg, sc administered once daily treatment started from postnatal day 6 to 12 days	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
13.	ALA5163580	T	Toxicity in wild type mouse assessed as effect on kidney size	Mus musculus	10	ALA5154831	tissue-based format	Scientific Literature
14.	ALA5163581	T	Toxicity in wild type mouse assessed as effect on body weight	Mus musculus	10	ALA5154831	assay format	Scientific Literature
15.	ALA5163582	F	Invivo antagonist activity at V2R in Pkd1 knockout mouse model of autosomal dominant polycystic kidney disease assessed as reduction of renal cyst formation 2 mg/kg, sc administered once daily treatment started from postnatal day 6 to 12 days by hematoxylin and eosin staining based assay	Mus musculus	3	ALA5154831	organism-based format	Scientific Literature
16.	ALA5163583	A	Elimination rate constant in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
17.	ALA5163584	A	Half life in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
18.	ALA5163585	A	Tmax in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
19.	ALA5163586	A	Cmax in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
20.	ALA5163587	A	AUC (0 to t) in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature