| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5140474 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5140475 | T | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at upto 25 uM measured after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5140476 | F | Antioxidant activity assessed as NO radical scavenging activity at 1.5625 to 25 uM incubated for 5 hrs in presence of sodium nitroprusside by griess reagent based assay | 1 | assay format | Scientific Literature | |||
| 4. | ALA5140477 | F | Inhibition of TNF-alpha production in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5140478 | F | Inhibition of IL-1beta production in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5140479 | F | Inhibition of IL-6 production in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5140480 | F | Inhibition of PGE2 production in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5140481 | F | Inhibition of IL-1beta mRNA expression in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by qRT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5140482 | F | Inhibition of IL-6 mRNA expression in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by qRT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5140483 | F | Inhibition of COX-2 mRNA expression in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by qRT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5140484 | F | Downregulation of iNOS protein expression in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5140485 | F | Downregulation of COX-2 protein expression in LPS-stimulated mouse RAW264.7 cells measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5140486 | B | Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells assessed as upregulation of IkappaBalpha protein expression at 3.125 to 12.5 uM preincubated for 24 hrs followed by LPS addition and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5140487 | B | Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells assessed as reduction in p65 expression in cytoplasm at 3.125 to 12.5 uM preincubated for 24 hrs followed by LPS addition and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5140488 | B | Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells assessed as reduction in p65 expression in nucleus at 3.125 to 12.5 uM preincubated for 24 hrs followed by LPS addition and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5140489 | B | Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells assessed as reduction in translocation of p65 from cytoplasm to nucleus at 3.125 to 12.5 uM preincubated for 24 hrs followed by LPS addition and measured after 30 mins by immunofluorescence analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5140490 | B | Inhibition of Akt phosphorylation in LPS-stimulated mouse RAW264.7 cells at 3.125 to 12.5 uM measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5140491 | B | Inhibition of JNK phosphorylation in LPS-induced mouse RAW264.7 cells measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5140492 | B | Inhibition of ERK phosphorylation in LPS-induced mouse RAW264.7 cells at 3.125 to 12.5 uM measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5140493 | B | Inhibition of p38 phosphorylation in LPS-induced mouse RAW264.7 cells at 3.125 to 12.5 uM measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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