| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5122272 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with sun light for 0.5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA5122273 | F | Antiproliferative activity against human SK-MEL-2 cells harboring wild type B-RAF assessed as cell growth inhibition irradiated with 365 nm UV light for 5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA5122274 | B | Inhibition of GST-tagged recombinant human B-RAF V600E mutant expressed in baculovirus expression system incubated for 1 hr in presence of ATP by FRET-based Z'-Lyte analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA5122275 | P | Retention time of compound in PBS buffer by UPLC analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA5122276 | F | Photorelease ability in PBS buffer assessed as N-(2,4-difluoro-3-((3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)phenyl)pyridine-3-sulfonamide formation by measuring half life at 5.85 ug/ml irradiated with 365 nm UV light by UPLC analysis | 1 | assay format | Scientific Literature | |||
| 6. | ALA5122277 | P | Photo conversion in PBS buffer assessed as N-(2,4-difluoro-3-((3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)phenyl)-pyridine-3-sulfonamide formation at 5.85 ug/ml irradiated with 365 nm UV light for 6 mins by UPLC analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA5122278 | F | Photorelease ability in PBS buffer assessed as N-(2,4-difluoro-3-((3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)phenyl)pyridine-3-sulfonamide formation by measuring half life at 5.85 ug/ml irradiated with sun light by UPLC analysis | 1 | assay format | Scientific Literature | |||
| 8. | ALA5122279 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA5122280 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with 365 nm UV light for 0.5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA5122281 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with 365 nm UV light for 2.5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA5122282 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with 365 nm UV light for 5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA5122283 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with 365 nm UV light for 10 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA5122284 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with sun light for 2.5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA5122285 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with sun light for 5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA5122286 | F | Antiproliferative activity against human A-375 cells harboring B-RAF V600E mutant assessed as cell growth inhibition irradiated with sun light for 10 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA5122287 | F | Antiproliferative activity against human SK-MEL-1 cells harboring wild type B-RAF assessed as cell growth inhibition measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5122288 | F | Antiproliferative activity against human SK-MEL-1 cells harboring wild type B-RAF assessed as cell growth inhibition irradiated with 365 nm UV light for 5 mins measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA5122289 | F | Antiproliferative activity against human SK-MEL-2 cells harboring wild type B-RAF assessed as cell growth inhibition measured after 72 hrs by CCK-8 analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA5122290 | B | Inhibition of ERK phosphorylation in human A-375 cells at 0.1 to 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA5122291 | B | Inhibition of ERK phosphorylation in human A-375 cells at 0.1 to 10 uM incubated for 2 hrs irradiated with 365 nm UV light for 5 mins by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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