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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5106610 Binding Inhibition of human caspase-3 using Ac-Asp-Glu-Val-Asp-pNA as substrate incubated for 60 mins by FRET assay Homo sapiens 2 ALA5104177 single protein format Scientific Literature 2. ALA5106611 Binding Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate addition and measured every 10 sec for 10 mins by FRET assay Severe acute respiratory syndrome coronavirus 2 16 ALA5104177 single protein format Scientific Literature 3. ALA5106612 Binding Inhibition of human Cathepsin L using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assay Homo sapiens 5 ALA5104177 single protein format Scientific Literature 4. ALA5106613 Binding Inhibition of human Cathepsin F using Z-Phe-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assay Homo sapiens 3 ALA5104177 single protein format Scientific Literature 5. ALA5106614 Binding Inhibition of human Cathepsin K using Ac-LR-AMC as fluorogenic substrate incubated for 60 mins by FRET assay Homo sapiens 3 ALA5104177 single protein format Scientific Literature 6. ALA5106615 Binding Inhibition of human Cathepsin B using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assay Homo sapiens 3 ALA5104177 single protein format Scientific Literature 7. ALA5106617 Functional Antiviral activity against SARS-CoV-2 infected in Vero E6 cells assessed as inhibition of viral replication incubated for 25 to 26 hrs by EliSpot reader based analysis Severe acute respiratory syndrome coronavirus 2 9 ALA5104177 organism-based format Scientific Literature 8. ALA5106618 Toxicity Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability incubated for 26 hrs by celltiter 96 aqueous non-radioactive cell proliferation assay Chlorocebus sabaeus 7 ALA5104177 cell-based format Scientific Literature 9. ALA5106621 Binding Inhibition of SARS-CoV-1 main protease Severe acute respiratory syndrome-related coronavirus 5 ALA5104177 assay format Scientific Literature 10. ALA5106623 ADME Microsomal stability in human liver microsomes assessed as intrinsic clearance at 1 uM preincubated for 10 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis Homo sapiens 1 ALA5104177 microsome format Scientific Literature 11. ALA5106624 ADME Half life in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 12. ALA5106625 ADME Tmax in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 13. ALA5106626 ADME Cmax in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 14. ALA5106627 ADME C0 in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 15. ALA5106628 ADME AUC (0 to t) in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 16. ALA5106629 ADME AUC (0 to infinity) in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 17. ALA5106630 ADME Half life in Sprague-Dawley rat at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 18. ALA5106631 ADME MRT (0 to infinity) in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 19. ALA5106632 ADME Clearance in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature 20. ALA5106633 ADME Tmax in Sprague-Dawley rat at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5104177 organism-based format Scientific Literature