# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5139763 | B | Inhibition of N-terminal human TRKA (436 to 790 residues) expressed in baculovirus expression system using TK as substrate measured after 30 mins in presence of ATP by HTRF assay | Homo sapiens | 39 | ALA5137027 | assay format | Scientific Literature | |
2. | ALA5139764 | B | Inhibition of N-terminal human TRKB (456 to 822 residues) expressed in baculovirus expression system using TK as substrate measured after 40 mins in presence of ATP by HTRF assay | Homo sapiens | 7 | ALA5137027 | assay format | Scientific Literature | |
3. | ALA5139765 | B | Inhibition of N-terminal human TRKC (456 to 825 residues) expressed in baculovirus expression system using TK as substrate measured after 40 mins in presence of ATP by HTRF assay | Homo sapiens | 7 | ALA5137027 | assay format | Scientific Literature | |
4. | ALA5139771 | F | Antiproliferative activity against human KM12 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Homo sapiens | 9 | ALA5137027 | cell-based format | Scientific Literature | |
5. | ALA5139772 | F | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA5137027 | cell-based format | Scientific Literature | |
6. | ALA5139773 | F | Antiproliferative activity against human THLE-2 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA5137027 | cell-based format | Scientific Literature | |
7. | ALA5139774 | F | Antiproliferative activity against mouse BaF3 cells harboring TRKA G595R mutant assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Mus musculus | 9 | ALA5137027 | cell-based format | Scientific Literature | |
8. | ALA5139873 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA5137027 | cell-based format | Scientific Literature |