| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5114542 | F | Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 29 | ALA5113390 | cell-based format | Scientific Literature | |
| 2. | ALA5114543 | F | Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5113390 | cell-based format | Scientific Literature | |
| 3. | ALA5114544 | F | Antiproliferative activity against human SNU-387 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5113390 | cell-based format | Scientific Literature | |
| 4. | ALA5114545 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5113390 | cell-based format | Scientific Literature | |
| 5. | ALA5114546 | F | Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5113390 | cell-based format | Scientific Literature | |
| 6. | ALA5114547 | F | Antiproliferative activity against human BEL-7402/5-FU cells overexpressing 14-3-3 eta assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5113390 | cell-based format | Scientific Literature | |
| 7. | ALA5114548 | B | Binding affinity to 14-3-3 eta (unknown origin) assessed as dissociation constant by biolayer interferometry assay | Homo sapiens | 18 | ALA5113390 | single protein format | Scientific Literature | |
| 8. | ALA5114549 | B | Inhibition of 14-3-3 eta in human Hep3B cells assessed as reduction in ERK phosphorylation measured after 24 hrs by western blot analysis | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 9. | ALA5114550 | B | Inhibition of 14-3-3 eta in human Hep3B cells assessed as reduction in AKT phosphorylation at T308 residue measured after 24 hrs by western blot analysis | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 10. | ALA5114551 | B | Inhibition of 14-3-3 eta in human Hep3B cells assessed as reduction in AKT phosphorylation at S473 residue measured after 24 hrs by western blot analysis | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 11. | ALA5114552 | F | Downregulation of AKT expression in human Hep3B cells measured after 24 hrs by western blot analysis | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 12. | ALA5114553 | F | Downregulation of ERK expression in human Hep3B cells at 0.5 to 5 uM measured after 24 hrs by western blot analysis | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 13. | ALA5114554 | F | Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability measured after 7 days by crystal violet staining based assay | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 14. | ALA5114555 | F | Inhibition of cell invasion in human Hep3B cells incubated for 72 hrs by crystal violet staining based transwell assay | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 15. | ALA5114556 | F | Induction of apoptosis in human Hep3B cells assessed as viable cells at 1 uM measured after 48 hrs by Annexin V/FITC-PI staining based flow cytometry assay (Rvb = 90.09%) | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 16. | ALA5114557 | F | Induction of apoptosis in human Hep3B cells assessed as early apoptotic cells at 1 uM measured after 48 hrs by Annexin V/FITC-PI staining based flow cytometry assay (Rvb = 6.65%) | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 17. | ALA5114558 | F | Induction of apoptosis in human Hep3B cells assessed as late apoptotic cells at 1 uM measured after 48 hrs by Annexin V/FITC-PI staining based flow cytometry assay (Rvb = 3.14%) | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 18. | ALA5114559 | F | Induction of apoptosis in human Hep3B cells assessed as necrotic cells at 1 uM measured after 48 hrs by Annexin V/FITC-PI staining based flow cytometry assay (Rvb = 0.12%) | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 19. | ALA5114560 | F | Induction of apoptosis in human Hep3B cells assessed as viable cells at 2.5 uM measured after 48 hrs by Annexin V/FITC-PI staining based flow cytometry assay (Rvb = 90.09%) | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature | |
| 20. | ALA5114561 | F | Induction of apoptosis in human Hep3B cells assessed as early apoptotic cells at 2.5 uM measured after 48 hrs by Annexin V/FITC-PI staining based flow cytometry assay (Rvb = 6.65%) | Homo sapiens | 1 | ALA5113390 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!