# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5117226 | B | Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units at 10 uM incubated for 24 hrs by luciferase reporter assay relative to control | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
2. | ALA5117227 | B | Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for 24 hrs by luciferase reporter assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
3. | ALA5117228 | F | Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA5117229 | F | Upregulation of axin-1 levels in human K562 cells by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA5117230 | F | Downregulation of beta-catenin levels in human K562 cells by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5117231 | P | Aqueous solubility of the compound in PBS buffer at pH 7.4 incubated for 6 hrs by HPLC analysis | 5 | small-molecule physicochemical format | Scientific Literature |