# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5142145 | B | Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor stably expressing in human HEK293 cell membranes under dark condition by radioligand based competition binding assay | Homo sapiens | 5 | cell membrane format | Scientific Literature | ||
2. | ALA5142146 | B | Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor stably expressing in human HEK293 cell membranes in presence of light-activated compounds by radioligand based competition binding assay | Homo sapiens | 4 | cell membrane format | Scientific Literature | ||
3. | ALA5142148 | B | Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor stably expressing in human HEK293 cell membranes under dark condition by radioligand based competition binding assay | Homo sapiens | 5 | cell membrane format | Scientific Literature | ||
4. | ALA5142149 | B | Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor stably expressing in human HEK293 cell membranes in presence of light-activated compounds by radioligand based competition binding assay | Homo sapiens | 4 | cell membrane format | Scientific Literature | ||
5. | ALA5142150 | F | Agonist activity at human melatonin MT1 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins under dark condition by cAMP assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA5142151 | F | Agonist activity at human melatonin MT1 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins in presence of light-activated compounds by cAMP assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA5142154 | F | Agonist activity at human melatonin MT2 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins under dark condition by cAMP assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA5142155 | F | Agonist activity at human melatonin MT2 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins in presence of light-activated compounds by cAMP assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA5142156 | F | Agonist activity at human melatonin MT2 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by measuring maximal efficacy after 30 mins under dark condition by cAMP assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5142159 | F | Effect on heterogenic neuronal polarization in Sprague-Dawley rat brain SCN neurons at 1 uM in presence of light activated compound by whole-cell patch clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature |