| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5122827 | B | Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substrate by fluorescence based analysis | Homo sapiens | 12 | ALA5120830 | assay format | Scientific Literature | |
| 2. | ALA5122828 | B | Inhibition of recombinant human AKR1C2 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production at 100 uM using S-tetralol as substrate by fluorescence based analysis relative to control | Homo sapiens | 9 | ALA5120830 | assay format | Scientific Literature | |
| 3. | ALA5122831 | B | Selectivity index, ratio of inhibition of recombinant human AKR1C2 transfected in Escherichia coli BL21 (DE) to IC50 for inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) | Homo sapiens | 3 | ALA5120830 | assay format | Scientific Literature | |
| 4. | ALA5122832 | P | Solubility of the compound in PBS at pH 7.4 incubated for 24 hrs by UHPLC analysis | 12 | ALA5120830 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA5122833 | F | Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 12 | ALA5120830 | cell-based format | Scientific Literature | |
| 6. | ALA5122836 | P | Lipophilicity, logD of the compound in n-octanol and phosphate buffer at pH 7.4 incubated for 4 hrs by UV-Vis spectrophotometer based shake flask method | 12 | ALA5120830 | small-molecule physicochemical format | Scientific Literature |
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