# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5164189 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as induction of AR degradation at 1 to 10 uM measured after 16 hrs by western blot analysis | Homo sapiens | 12 | ALA5154850 | cell-based format | Scientific Literature | |
2. | ALA5164190 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as induction of AR degradation at 1 uM measured after 16 hrs by western blot analysis relative to control | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
3. | ALA5164191 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as induction of AR degradation at 10 uM measured after 16 hrs by western blot analysis relative to control | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
4. | ALA5164192 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as induction of AR degradation at 0.01 to 1 uM measured after 16 hrs by western blot analysis | Homo sapiens | 3 | ALA5154850 | cell-based format | Scientific Literature | |
5. | ALA5164193 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as reduction in AR level at 100 nM measured after 6 hrs by western blot analysis | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
6. | ALA5164194 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as induction of AR degradation measured after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
7. | ALA5164195 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as AR degradation at 100 nM measured in presence of 0.5 uM MLN4924 after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
8. | ALA5164196 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as AR degradation at 100 nM measured in presence of 10 uM VHL ligand after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
9. | ALA5164197 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as AR degradation at 100 nM measured in presence of 10 uM AR ligand after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature | |
10. | ALA5164198 | B | PROTAC activity at VHL/AR in human LNCaP cells assessed as AR degradation at 100 nM measured in presence of 5 uM MG132 after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA5154850 | cell-based format | Scientific Literature |