# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166085 | B | Inhibition of ERK5 (unknown origin) using K-5FAM-LVEPLTPSGEAPNQ-COOH as substrate incubated for 2 hrs in presence of ATP by IMAP-FP assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
2. | ALA5166086 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 17 | microsome format | Scientific Literature | ||
3. | ALA5166088 | A | Apparent permeability of the compound across apical to basolateral side in human Caco-2 cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
4. | ALA5166089 | A | Efflux ratio of apparent permeability in human Caco-2 cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
5. | ALA5166090 | B | Inhibition of ERK5 phosphorylation in human HeLa cells incubated for 1 hr by Western blot densitometry analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
6. | ALA5166091 | A | Clearance in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
7. | ALA5166092 | A | Volume of distribution in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
8. | ALA5166093 | A | Half life in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
9. | ALA5166094 | A | Oral bioavailability in mouse at 10 mg/kg measured upto 60 min by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
10. | ALA5166126 | A | Terminal elimination half life in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature |