# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5151674 | B | Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence of ATP by ADP-GloTM assay | Homo sapiens | 26 | ALA5149995 | cell-based format | Scientific Literature | |
2. | ALA5151676 | B | Covalent binding affinity to NIK (unknown origin) assessed as labeling at Cys444 residue using Ala438-Arg451 peptide incubated for 18 hrs measured after tryptic digestion by MS/MS fragmentation spectral analysis | Homo sapiens | 2 | ALA5149995 | single protein format | Scientific Literature | |
3. | ALA5151687 | F | Antiproliferative activity against NIK-activated human Z138 cells assessed as inhibition of cell growth incubated for 72 hrs by XTT assay | Homo sapiens | 5 | ALA5149995 | cell-based format | Scientific Literature | |
4. | ALA5151688 | F | Antiproliferative activity against NIK-activated human MAVER-1 cells assessed as inhibition of cell growth incubated for 72 hrs by XTT assay | Homo sapiens | 5 | ALA5149995 | cell-based format | Scientific Literature | |
5. | ALA5151689 | F | Antiproliferative activity against NIK-independent human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by XTT assay | Homo sapiens | 5 | ALA5149995 | cell-based format | Scientific Literature | |
6. | ALA5151690 | F | Antiproliferative activity against NIK-independent human JIM3 cells assessed as inhibition of cell growth incubated for 72 hrs by XTT assay | Homo sapiens | 5 | ALA5149995 | cell-based format | Scientific Literature |