# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5164885 | B | Binding affinity to human galectin-3 using 2-(fluorescein-5/6-yl-carbonylamino)-ethyl 2-acetamido-2-deoxy-alpha-D-galactopyranosyl-(1-3)-[alpha-L-fucopyranosyl-(1-2)]-beta-D-galactopyranosyl-(1-4)-beta-D-glucopyranoside by fluorescence polarization analysis | Homo sapiens | 6 | ALA5154868 | single protein format | Scientific Literature | |
2. | ALA5164886 | B | Binding affinity to human galectin-4N expressed in Escherichia coli BL21 using 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-y1]-3'-(3,5-dimethoxy-benzamido)-1,1'-sulfanediyl-di-beta-D-galactopyranoside as fluorescent probe by fluorescence polarization analysis | Homo sapiens | 5 | ALA5154868 | assay format | Scientific Literature | |
3. | ALA5164887 | B | Binding affinity to human galectin-4C using 2-(fluorescein-5/6-yl-carbonylamino)-ethyl 2-acetamido-2-deoxy-alpha-D-galactopyranosyl-(1-3)-[alpha-L-fucopyranosyl-(1-2)]-beta-D-galactopyranosyl-(1-4)-beta-D-glucopyranoside as fluorescent probe by fluorescence polarization analysis | Homo sapiens | 6 | ALA5154868 | single protein format | Scientific Literature | |
4. | ALA5164890 | B | Antagonist activity against human galectin-8N assessed as inhibition of galectin-8N at 2 mM by fluorescence polarization analysis relative to control | Homo sapiens | 5 | ALA5154868 | single protein format | Scientific Literature | |
5. | ALA5164891 | B | Binding affinity to human galectin-1 C3S mutant by fluorescence polarization analysis | Homo sapiens | 1 | ALA5154868 | assay format | Scientific Literature | |
6. | ALA5164892 | F | Cytotoxicity against human TXL2 patient-derived BCP-ALL cells assessed as reduction in cell viability at 500 uM incubated for 2 hrs by trypan blue staining based assay | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
7. | ALA5164893 | F | Cytotoxicity against human US7 patient-derived BCP-ALL cells assessed as reduction in cell viability at 500 uM incubated for 2 hrs by trypan blue staining based assay | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
8. | ALA5164894 | B | Antagonist activity against human TXL2 patient-derived BCP-ALL cells assessed as inhibition of galectin-3-mediated agglutination at 500 uM incubated for 2 hrs by phase contrast microscopy | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
9. | ALA5164895 | B | Antagonist activity against human US7 patient-derived BCP-ALL cells assessed as inhibition of galectin-3-mediated agglutination at 500 uM incubated for 2 hrs by phase contrast microscopy | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
10. | ALA5164896 | F | Induction of cell death in human TXL2 patient-derived BCP-ALL cells assessed as reduction in viable cells at 0.5 to 800 uM incubated for 24 hrs by Alamar blue assay | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
11. | ALA5164897 | F | Induction of cell death in human US7 patient-derived BCP-ALL cells assessed as reduction in viable cells at 0.5 to 800 uM incubated for 24 hrs by Alamar blue assay | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
12. | ALA5164898 | F | Cytotoxicity against human US7 patient-derived BCP-ALL cells co-cultured with irradiated OP9 stromal cells assessed as reduction in cell viability incubated for 24 hrs by Alamar blue assay | Homo sapiens | 5 | ALA5154868 | cell-based format | Scientific Literature | |
13. | ALA5164899 | F | Cytotoxicity against human LAX40 patient-derived BCP-ALL cells co-cultured with irradiated OP9 stromal cells assessed as reduction in cell viability at 100 uM for 1 to 3 days by trypan blue staining based assay | Homo sapiens | 2 | ALA5154868 | cell-based format | Scientific Literature | |
14. | ALA5164900 | F | Cytostatic activity against human LAX40 patient-derived BCP-ALL cells co-cultured with irradiated OP9 stromal cells assessed as reduction in cell viability at 100 uM for 1 to 3 days by trypan blue staining based assay | Homo sapiens | 2 | ALA5154868 | cell-based format | Scientific Literature | |
15. | ALA5164906 | T | Cytotoxicity against mouse bone marrow-derived stromal OP9 cells assessed as live cells at 100 uM measured after 3 days by trypan blue staining based assay relative to control | Mus musculus | 1 | ALA5154868 | cell-based format | Scientific Literature | |
16. | ALA5164908 | B | Antagonist activity against human TXL2 patient-derived BCP-ALL cells assessed as inhibition of galectin-1-mediated cell-cell cluster formation at 500 uM incubated for 2 hrs by phase contrast microscopy | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature | |
17. | ALA5164909 | B | Antagonist activity against human US7 patient-derived BCP-ALL cells assessed as inhibition of galectin-1-mediated cell-cell cluster formation at 500 uM incubated for 2 hrs by phase contrast microscopy | Homo sapiens | 1 | ALA5154868 | cell-based format | Scientific Literature |