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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5165263 | Functional | Antimetastatic activity against human MDA-MB-231 cells xenografted in BALB/c mouse assessed as downregulation of MMP-9 at 30 uM incubated for 2 to 12 hrs by western blot analysis | Homo sapiens | 2 | ALA5154877 | cell-based format | Scientific Literature | |
2. | ALA5165264 | Functional | Antimetastatic activity against human MDA-MB-231 cells xenografted in BALB/c mouse assessed as decrease in plasma S1P levels at 50 mg/kg, ip for 28 days | Homo sapiens | 1 | ALA5154877 | organism-based format | Scientific Literature | |
3. | ALA5165265 | Binding | Inhibition of SPHK2 (unknown origin) using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assay | Homo sapiens | 12 | ALA5154877 | single protein format | Scientific Literature | |
4. | ALA5165266 | Binding | Inhibition of SPHK1 (unknown origin) at 10 uM using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assay relative to control | Homo sapiens | 26 | ALA5154877 | single protein format | Scientific Literature | |
5. | ALA5165267 | Binding | Inhibition of SPHK1 (unknown origin) using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assay | Homo sapiens | 12 | ALA5154877 | single protein format | Scientific Literature | |
6. | ALA5165268 | Binding | Inhibition of VEGFR1 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
7. | ALA5165269 | Binding | Inhibition of VEGFR2 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
8. | ALA5165270 | Binding | Inhibition of VEGFR3 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
9. | ALA5165271 | Binding | Inhibition of PDGFRalpha (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
10. | ALA5165272 | Binding | Inhibition of PDGFRbeta (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
11. | ALA5165273 | Binding | Inhibition of RET (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
12. | ALA5165274 | Binding | Inhibition of FLT3 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
13. | ALA5165275 | Binding | Inhibition of EGFR (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
14. | ALA5165276 | Binding | Inhibition of ERBB2 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
15. | ALA5165277 | Binding | Inhibition of ERBB4 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
16. | ALA5165278 | Binding | Inhibition of SRC (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
17. | ALA5165279 | Binding | Inhibition of ABL (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
18. | ALA5165280 | Binding | Inhibition of EPHA2 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
19. | ALA5165281 | Binding | Inhibition of EPHB2 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature | |
20. | ALA5165282 | Binding | Inhibition of ACK1 (unknown origin) | Homo sapiens | 2 | ALA5154877 | single protein format | Scientific Literature |