# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5131290 | B | Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recording | Homo sapiens | 22 | ALA5126674 | cell-based format | Scientific Literature | |
2. | ALA5131291 | B | Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recording | Homo sapiens | 22 | ALA5126674 | cell-based format | Scientific Literature | |
3. | ALA5131293 | B | Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell patch clamp electrophysiology recording | Homo sapiens | 12 | ALA5126674 | cell-based format | Scientific Literature | |
4. | ALA5131294 | B | Inhibition of human Nav1.6 expressed in HEK293 cells by whole cell patch clamp electrophysiology recording | Homo sapiens | 13 | ALA5126674 | cell-based format | Scientific Literature | |
5. | ALA5131297 | B | Inhibition of human Nav1.1 expressed in HEK293 cells at -120 mV holding potential by automated patch clamp electrophysiology recording | Homo sapiens | 1 | ALA5126674 | cell-based format | Scientific Literature | |
6. | ALA5131298 | B | Inhibition of human Nav1.2 expressed in CHO cells at -120 mV holding potential by automated patch clamp electrophysiology recording | Homo sapiens | 1 | ALA5126674 | cell-based format | Scientific Literature | |
7. | ALA5131299 | B | Inhibition of human Nav1.3 expressed in CHO cells at -120 mV holding potential by automated patch clamp electrophysiology recording | Homo sapiens | 1 | ALA5126674 | cell-based format | Scientific Literature | |
8. | ALA5131300 | B | Inhibition of human Nav1.8 expressed in CHO cells at -120 mV holding potential by automated patch clamp electrophysiology recording | Homo sapiens | 1 | ALA5126674 | cell-based format | Scientific Literature | |
9. | ALA5131301 | T | Inhibition of hERG | Homo sapiens | 1 | ALA5126674 | assay format | Scientific Literature | |
10. | ALA5131302 | B | Inhibition of Cav1.2 (unknown origin) | Homo sapiens | 1 | ALA5126674 | single protein format | Scientific Literature | |
11. | ALA5131305 | A | Intrinsic clearance in human liver microsomes assessed per mg protein | Homo sapiens | 1 | ALA5126674 | microsome format | Scientific Literature | |
12. | ALA5131306 | A | Intrinsic clearance in rat liver microsomes assessed per mg protein | Rattus norvegicus | 1 | ALA5126674 | microsome format | Scientific Literature | |
13. | ALA5131307 | A | Intrinsic clearance in human hepatocytes assessed per million cells | Homo sapiens | 1 | ALA5126674 | cell-based format | Scientific Literature | |
14. | ALA5131308 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA5126674 | single protein format | Scientific Literature | |
15. | ALA5131309 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA5126674 | single protein format | Scientific Literature | |
16. | ALA5131310 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA5126674 | single protein format | Scientific Literature | |
17. | ALA5131311 | A | Apparent permeability from apical to basolateral side in MDCK cells | Canis lupus familiaris | 1 | ALA5126674 | cell-based format | Scientific Literature | |
18. | ALA5131312 | A | Unbound fraction in human plasma | Homo sapiens | 1 | ALA5126674 | cell-free format | Scientific Literature | |
19. | ALA5131313 | A | Unbound fraction in Cynomolgous monkey plasma | Macaca fascicularis | 1 | ALA5126674 | cell-free format | Scientific Literature | |
20. | ALA5131314 | A | Clearance in rat plasma | Rattus norvegicus | 1 | ALA5126674 | cell-free format | Scientific Literature |