| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5163165 | F | Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(7-36)NH2 induced cAMP accumulation at 10 uM preincubated for 15 mins followed by GLP-1(7-36)NH2 addition and measured after 15 mins relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 2. | ALA5163168 | B | Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion at 1 uM incubated for 30 mins in presence of 15 mM of glucose by ELISA | Rattus norvegicus | 4 | cell-based format | Scientific Literature |
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